dc.contributor.author | Aluisio, AR | |
dc.contributor.author | Bosire, R | |
dc.contributor.author | Bourke, B | |
dc.contributor.author | Gatuguta, A | |
dc.contributor.author | Kiarie, JN | |
dc.contributor.author | Nduati, R | |
dc.contributor.author | John-Stewart, G | |
dc.contributor.author | Farquhar, C | |
dc.date.accessioned | 2017-03-20T07:56:44Z | |
dc.date.available | 2017-03-20T07:56:44Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Aluisio, Adam R., et al. "Male partner participation in antenatal clinic services is associated with improved HIV-free survival among infants in Nairobi, Kenya: a prospective cohort study." JAIDS Journal of Acquired Immune Deficiency Syndromes 73.2 (2016): 169-176. | en_US |
dc.identifier.uri | https://www.ncbi.nlm.nih.gov/pubmed/27124363 | |
dc.identifier.uri | http://hdl.handle.net/11295/100613 | |
dc.description.abstract | OBJECTIVE:
This prospective study investigated the relationship between male antenatal clinic (ANC) involvement and infant HIV-free survival.
METHODS:
From 2009 to 2013, HIV-infected pregnant women were enrolled from 6 ANCs in Nairobi, Kenya and followed with their infants until 6 weeks postpartum. Male partners were encouraged to attend antenatally through invitation letters. Men who failed to attend had questionnaires sent for self-completion postnatally. Multivariate regression was used to identify correlates of male attendance. The role of male involvement in infant outcomes of HIV infection, mortality, and HIV-free survival was examined.
RESULTS:
Among 830 enrolled women, 519 (62.5%) consented to male participation and 136 (26.2%) men attended the ANC. For the 383 (73.8%) women whose partners failed to attend, 63 (16.4%) were surveyed through outreach. In multivariate analysis, male report of previous HIV testing was associated with maternal ANC attendance (adjusted odds ratio = 3.7; 95% CI: 1.5 to 8.9, P = 0.003). Thirty-five (6.6%) of 501 infants acquired HIV or died by 6 weeks of life. HIV-free survival was significantly greater among infants born to women with partner attendance (97.7%) than those without (91.3%) (P = 0.01). Infants lacking male ANC engagement had an approximately 4-fold higher risk of death or infection compared with those born to women with partner attendance (HR = 3.95, 95% CI: 1.21 to 12.89, P = 0.023). Adjusting for antiretroviral use, the risk of death or infection remained significantly greater for infants born to mothers without male participation (adjusted hazards ratio = 3.79, 95% CI: 1.15 to 12.42, P = 0.028).CONCLUSIONS:
Male ANC attendance was associated with improved infant HIV-free survival. Promotion of male HIV testing and engagement in ANC/prevention of mother-to-child transmission services may improve infant outcomes. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Nairobi | en_US |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
dc.title | Male partner participation in antenatal clinic services is associated with improved Hiv-free survival among infants in Nairobi, Kenya: a prospective cohort study. | en_US |
dc.type | Article | en_US |