Now showing items 1-6 of 6
The role of G Protein Gene GNB3 C825T Polymorphism in HIV-1 acquisition, progression and immune activation
Abstract Background The GNB3 C825T polymorphism is associated with increased G protein-mediated signal transduction, SDF-1α-mediated lymphocyte chemotaxis, accelerated HIV-1 progression, and altered responses to ...
Uptake of prevention of mother to child transmission interventions in Kenya: health systems are more influential than stigma
Abstract Background We set out to determine the relative roles of stigma versus health systems in non-uptake of prevention of mother to child transmission (PMTCT) of HIV-1 interventions: we conducted cross-sectional ...
Medication diaries do not improve outcomes with highly active antiretroviral therapy in Kenyan children: a randomized clinical trial
Abstract Background As highly active antiretroviral therapy (HAART) becomes increasingly available to African children, it ...
Predictors of mortality in HIV-1 infected children on antiretroviral therapy in Kenya: a prospective cohort
Abstract Background Among children, early mortality following highly active antiretroviral therapy (HAART) remains high. It ...
Evaluation of a single round polymerase chain reaction assay using dried blood spots for diagnosis of HIV-1 infection in infants in an African setting
Abstract Background The aim of this study was to develop an economical 'in-house' single round polymerase chain reaction (PCR) assay using filter paper-dried blood spots (FP-DBS) for early infant HIV-1 diagnosis ...