Human herpesvirus 8: seroprevalence and correlates in prostitutes in Mombasa, Kenya
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Date
2003Author
Lavreys, L
Chohan, B
Ashley, R
Richardson, BA
Corey, L
Mandaliya, K
Ndinya-Achola Jeckoniah O.
Kreiss, JK
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Human herpesvirus 8 (HHV-8) infection is very prevalent in sub-Saharan Africa, but the role of sexual transmission has not been well characterized. HHV-8 seroprevalence and correlates were evaluated in a cohort of female prostitutes in Mombasa, Kenya. Between February 1993 and January 2000, stored plasma samples taken from 736 women were tested, by whole-virus ELISA assay, for the presence of HHV-8 antibodies; of these 736 women, 633 were included in the analysis of correlates of HHV-8 infection; and, of these 633, 44.1% were seropositive for HHV-8 antibodies. In univariate analysis, age, years of education, years of prostitution, workplace, hormonal contraception, intrauterine-device use, alcohol consumption, syphilis, and gonorrhea were all significantly associated with the presence of HHV-8 antibodies. In a multivariate model, older age, fewer years of education, and 2 markers of high-risk sexual behavior-namely, alcohol consumption and gonorrhea-were each independently associated with HHV-8 seropositivity. These results suggest that heterosexual transmission may contribute to acquisition of HHV-8 infections in this African population of prostitutes
URI
http://www.ncbi.nlm.nih.gov/pubmed/12552419http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16709
Citation
J Infect Dis. 2003 Feb 1;187(3):359-63Publisher
Department of Epidemiology, University of Washington, Seattle, Washington, USA Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada Department of Medical Microbiology, University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10377]