Infectious agents and lymphoma
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Date
2011-05Author
De Falco G.
Leoncini L.
Rogena Emily Adhiambo.
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
In the past 25 years revelations on the genesis of human cancer have come at an increasing pace. Research on oncogenic infectious agents, especially viruses, has helped us to understand the process of malignant transformation of cells because the cellular events in viral-driven transformation mirror, often brilliantly, basic cellular processes that culminate in cancer, even those not associated with viruses. Infectious agents, especially viruses, account for several of the most common malignancies-up to 20% of all cancers. Some of these cancers are endemic, with a high incidence in certain geographic locations, but sporadic/lower incidence in other parts of the world. Lymphomas arise frequently in association with infectious agents such as Epstein-Barr virus, human immunodeficiency virus, human herpes virus 8, Helicobacter pylori, and hepatitis C virus. In this review, we will focus on the association between infectious agents and lymphomas, with a look at the molecular mechanisms they use to disturb cell regulation and eventually result in cancer.
URI
http://www.ncbi.nlm.nih.gov/pubmed/21842703http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16840
Citation
Semin Diagn Pathol.Collections
- Faculty of Health Sciences (FHS) [10377]