dc.contributor.author | Mostad, S B | |
dc.contributor.author | Kreiss, J K | |
dc.contributor.author | Ryncarz, A J | |
dc.contributor.author | Mandaliya, K | |
dc.contributor.author | Chohan, B | |
dc.contributor.author | Ndinya-Achola, JO | |
dc.contributor.author | Bwayo, JJ | |
dc.contributor.author | Corey, L | |
dc.date.accessioned | 2013-05-31T07:42:16Z | |
dc.date.available | 2013-05-31T07:42:16Z | |
dc.date.issued | 2000-01 | |
dc.identifier.citation | Mostad Sb, Kreiss Jk, Ryncarz Aj, Mandaliya K, Chohan B, Ndinya-achola J, Bwayo Jj, Corey L.cervical Shedding Of Herpes Simplex Virus In Human Immunodeficiency Virus-infected Women: Effects Of Hormonal Contraception, Pregnancy, And Vitamin A Deficiency. J, O., Prof. Ndinya-achola J. , J Infect Dis. 2000 Jan;181(1):58-63., (2000) | en |
dc.identifier.uri | Http://profiles.uonbi.ac.ke/jndinya/publications/mostad-sb-kreiss-jk-ryncarz-aj-mandaliya-k-chohan-b-ndinya-achola-j-bwayo-jj-co | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/28089 | |
dc.description.abstract | { Genital shedding of herpes simplex virus (HSV) results in frequent transmission of infection to sexual partners and neonates. In a cross-sectional study, cervical shedding of HSV DNA was detected in 43 (17%) cervical swab samples from 273 women seropositive for HSV-1, HSV-2, and human immunodeficiency virus type 1 (HIV-1). Cervical shedding of HSV was significantly associated with oral contraception (adjusted odds ratio [aOR], 4.5; 95% confidence interval [CI], 1.7-12.2), use of depo-medroxyprogesterone acetate (aOR, 3.2; 95% CI, 1.3-7.7), and pregnancy (aOR, 7.9; 95% CI, 2.0-31.7). In the subgroup of women who were not pregnant and not using hormonal contraception (n=178), serum vitamin A was highly predictive of cervical HSV shedding: concentrations indicating severe deficiency, moderate deficiency, low-normal, and high-normal status were associated with 29%, 18%, 8%, and 2% prevalences of cervical HSV shedding, respectively (linear trend | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | Cervical Shedding Of Herpes Simplex Virus In Human Immunodeficiency Virus-infected Women: Effects Of Hormonal Contraception, Pregnancy, And Vitamin A Deficiency. J | en |
dc.type | Article | en |
local.publisher | Institute of Tropica and Infectious Diseases(UNITID) | en |