Group A streptococcal throat colonization is a dynamic phenomenon
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Date
2000-03Author
Dawson, KP
Nsanze, H
Ameen, AS
Mustafa, N
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
In order to gain knowledge about the nature of group A streptococcal throat colonization of asymptomatic children, we studied a cohort of healthy children selected at random. Those with throat cultures positive for group A Streptococci (GAS) were followed for 5 weeks. Repeat throat swabs were obtained at weekly intervals for antigen detection and culture. GAS obtained were serotyped for T antigen. Twenty-two children were identified as having GAS and 50% had a positive antigen test and culture at least five times in 6 weeks. There was no consistent pattern in the typeable organisms. Most individuals had more than one T-type alternating with non-T-typeable organisms. We conclude that colonization may be a dynamic process involving numerous organism serotypes, which wax and wane.
URI
http://www.ncbi.nlm.nih.gov/pubmed/10824208http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30974
Citation
Ann Trop Paediatr. 2000 Mar;20(1):16-21Publisher
University of Nairobi. Department of Medicine
Collections
- Faculty of Health Sciences (FHS) [10377]