Application of enzyme-linked immunosorbent assay (ELISA) based on two E. granulosus antigens in the diagnosis of human hydatidosis
Date
1989Author
Njeruh, F M
Gathura, P B
Gathuma, J M
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
A total of 180 sera consisting of 50 sera from Kenyans with surgically confirmed hydatidosis and 130 sera from individuals without hydatid disease were examined. "Antigen 880" (which is suspected to be similar to Antigen B) showed a sensitivity of 88%. No false reactions were obtained with sera from individuals with non-hydatid infections, hence a specificity of 100% was recorded with this antigen. "Antigen 346" (which is similar to Capron's "Arc 5") showed a sensitivity of 52% and a specificity of 100%. It is concluded that "Antigen 880" may be more useful than "Arc 5" in the diagnosis of human hydatidosis in Kenya due to the high sensitivity obtained with the antigen.
URI
http://europepmc.org/abstract/MED/2606016http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/33088
Citation
Njeruh, F. M, Gathura, P. B & Gathuma, J. M(1989). Application of enzyme-linked immunosorbent assay (ELISA) based on two E. granulosus antigens in the diagnosis of human hydatidosis. East African Medical Journal; 66(11): 738-742.Publisher
Department of Public Health, pharmacology and Toxicology, University of Nairobi
Subject
enzyme-linked immunosorbent assay (ELISA)E. granulosus antigens
Diagnosis
Human hydatidosis.
Description
Journal article