Protective Effect Of Whey Protein Hydrolysates Against Hydrogen Peroxide-induced Oxidative Stress On Pc12 Cells

dc.contributor.author	Zhang, Qiu-Xiang
dc.contributor.author	Ling, Yu-Fang
dc.contributor.author	Sun, Zhen
dc.contributor.author	Zhang, Li
dc.contributor.author	Yu, Hui-Xin
dc.contributor.author	Kamau, Samuel Mburu
dc.contributor.author	Lu, Rong-Rong
dc.date.accessioned	2013-06-24T08:07:16Z
dc.date.available	2013-06-24T08:07:16Z
dc.date.issued	2012-11
dc.identifier.citation	Biotechnology Letters November 2012, Volume 34, Issue 11, pp 2001-2006	en
dc.identifier.uri	http://link.springer.com/article/10.1007/s10529-012-1017-1
dc.identifier.uri	http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/38750
dc.description.abstract	The protective effect of whey protein hydrolysates (WPHs) against H2O2-induced oxidative damage on rat pheochromocytoma line 12 (PC12) cells was studied. Whey protein was hydrolyzed by pepsin and trypsin and purified by macrospore absorption resins. PC12 cells were pretreated with WPHs (from 369 to 1,980 Da) at different concentrations for 2 h, then washed and incubated with 100 μM H2O2 in the presence of WPHs for another 24 h. With 100–400 μg WPH/ml the viable cells increased by 20–30 % when incubated with H2O2 suggesting that they may play a role as antioxidant in foods.	en
dc.language.iso	en	en
dc.publisher	University of Nairobi	en
dc.title	Protective Effect Of Whey Protein Hydrolysates Against Hydrogen Peroxide-induced Oxidative Stress On Pc12 Cells	en
dc.type	Article	en
local.publisher	College of Humanities and Social Sciences	en