Single-dose ceftriaxone therapy of gonococcal ophthalmia neonatorum
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Date
1986-01Author
Haase, DA
Nash, RA
Nsanze, H
D'Costa, LJ
Fransen, L
Piot, P
Brunham, RC
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Ceftriaxone (125 mg) given as a single intramuscular dose without topical therapy was evaluated in seven infants with smear-positive gonococcal ophthalmia neonatorum. Neisseria gonorrhoeae was isolated from the eyes of six infants, and four of these isolates were penicillinase-producing N. gonorrhoeae. Two infants had concomitant ocular infection with Chlamydia trachomatis. All seven infants, when seen at follow-up, showed marked clinical improvement. Conjunctivitis resolved completely in four infants. One infant was lost to subsequent follow-up, while two infants had persistent ophthalmia due to C. trachomatis. Follow-up eye cultures for N. gonorrhoeae were all negative.
URI
http://www.ncbi.nlm.nih.gov/pubmed/3082022http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/57604
Citation
Sex Transm Dis. 1986 Jan-Mar;13(1):53-5.Publisher
University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10377]