Search
Now showing items 1-7 of 7
Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort
(2008)
OBJECTIVE:
A group of commercial sex workers in the Pumwani Sex Worker Cohort, established in 1985 in Nairobi, Kenya, remain HIV-1 uninfected despite heavy exposure to HIV-1 through active sex work. Previous studies showed ...
Coinfection with herpes simplex virus type 2 is associated with reduced HIV-specific T cell responses and systemic immune activation.
(University of Nairobi,, 2008)
BACKGROUND:
Chronic coinfection with herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) has been associated with an increased HIV viral load and more rapid disease progression, perhaps related to ...
Mucosal Neisseria gonorrhoeae coinfection during HIV acquisition is associated with enhanced systemic HIV-specific CD8 T-cell responses
(2008)
Background: The host immune response against mucosally acquired pathogens may be
influenced by the mucosal immune milieu during acquisition. As Neisseria gonorrhoeae
can impair dendritic cell and T-cell immune function, ...
Reduced rates of HIV acquisition during unprotected sex by Kenyan female sex wo kers predating population declines in H IV prevalence
(2008)
OBJECTIVES:
Female sex workers (FSWs) form a core group at high risk of both sexual HIV acquisition and secondary transmission. The magnitude of these risks may vary by sexual risk taking, partner HIV prevalence, host ...
Human leukocyte antigen-DQ alleles and haplotypes and their associations with resistance and susceptibility to HIV-1 infection
(2008)
Objectives: To determine the association of DQ antigens with resistance and susceptibility
to HIV-1.
Design: Despite repeated exposure to HIV-1, a subset of women in the Pumwani Sex
Worker cohort established in Nairobi, ...
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers.
(University of Nairobi,, 2008-03)
OBJECTIVES:
HIV-neutralizing immunoglobulin A (IgA) and HIV-specific cellular immunity have been described in highly exposed, persistently seronegative (HEPS) individuals, but well controlled studies have not been performed. ...