Now showing items 1-10 of 18
Lack of efficacy of isoniazid chemoprophylaxis in the preventions of tuberculosis in hiv - 1 infected adults
Background: Six months of daily isoniazid has been shown to be effective in preventing tuberculosis in the pre-HIV era. Because of underlying immune dysfunction and increased susceptibility to new infection this efficacy ...
Resistance to HIV-1 infection among African sex workers is associated with global hyporesponsiveness in interleukin 4 production.
We previously identified HIV-1 resistant prostitutes who remain persistently HIV-1 PCR- and antibody-negative despite continued heavy exposure to HIV-1 through sex work. We hypothesized that differences in virus-specific ...
Sustained changes in sexual behavior by female sex workers after completion of a randomized HIV prevention trial
INTRODUCTION: Behavioral interventions in female sex workers (FSWs) are associated with changes in sexual behavior and reduced rates of sexually transmitted infections (STIs) and HIV We examined the sustainability of ...
Human Leucocyte Antigen Supertypes And Immune Susceptibility To Hiv-1, Implications
(University of Nairobi, 2001-11-01)
Evaluation of a low- dose nonoxynol-9 gel for the prevention of sexually transmitted diseases: a randomised clinical trial, Sex Transm Dis 2001
(University of Nairobi, 2001)
Objective: To assess the relation between selenium deficiency and vaginal or cervical shedding of HIV-1-infected cells. Design: Cross-sectional study of 318 HIV-1 seropositive women in Mombasa, Kenya. Methods: Vaginal and ...
Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial.
CONTEXT: Sexually transmitted infections (STIs) are common in female sex workers (FSWs) and may enhance susceptibility to infection with human immunodeficiency virus type 1 (HIV-1). OBJECTIVE: To examine regular ...
Role of Sexually Transmitted Infections in Accelerated HIV-1 Disease Progression
(University of nairobi, 2000)
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers.
(University of Nairobi,, 2008-03)
OBJECTIVES: HIV-neutralizing immunoglobulin A (IgA) and HIV-specific cellular immunity have been described in highly exposed, persistently seronegative (HEPS) individuals, but well controlled studies have not been performed. ...
Prevalent herpes simplex virus type 2 infection is associated with altered vaginal flora and an increased susceptibility to multiple sexually transmitted infections.
(University of Nairobi, 2007)
BACKGROUND: Prevalent herpes simplex virus type 2 (HSV-2) infection increases human immunodeficiency virus acquisition. We hypothesized that HSV-2 infection might also predispose individuals to acquire other common ...
Associations of sexual risk taking among Kenyan female sex workers after enrollment in an HIV-1 prevention trial.
BACKGROUND: Female sex workers (FSWs) often lack the ability to negotiate safer sex and are at high risk for HIV-1 infection and sexually transmitted infections (STIs). METHODS: Seronegative FSWs were enrolled in an ...