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Antiplasmodial activity of compounds from the surface exudates of Senecio roseiflorus
(University of Nairobi, 2013-02)
From the surface exudates of Senecio roseiflorus fourteen known methylated flavonoids and one phenol were isolated and characterized. The structures of these compounds were determined on the basis of their spectroscopic ...
Quality of hospital care for sick newborns and severely malnourished children in Kenya: A two-year descriptive study in 8 hospitals.
(2011-11-11)
Background
Given the high mortality associated with neonatal illnesses and severe malnutrition and the development of packages of interventions that provide similar challenges for service delivery mechanisms we set out ...
Effect of Amaranthus hybridus on the immunity of laboratory white albino rats
(2013)
This study determined the role of A. hybrids in boosting the immunity of female albino rats in the laboratory. They were
randomly assigned to four groups, A to D and followed for 16 weeks during which groups A to C had ...
Challenges for consent and community engagement in the conduct of cluster randomized trial among school children in low income settings: experiences from Kenya.
(University of Nairobi, 2013)
BACKGROUND:
There are a number of practical and ethical issues raised in school-based health research, particularly those related to obtaining consent from parents and assent from children. One approach to developing, ...
Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa
(University of nairobi, 2010)
Abstract
BACKGROUND:
We conducted a double-blind, randomized, placebo-controlled Phase I study of a recombinant replication-defective adenovirus type 5 (rAd5) vector expressing HIV-1 Gag and Pol from subtype B and Env ...
Mortality Projection: Curve Fitting And Linear Regression
(2011)
This study was aimed at predicting future mortality rates given two main scenarios. The first is in the
case where there is a body of mortality tables from the past and the second is in the case where such a
database ...
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
(2012)
BACKGROUND:
Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The prognostic value of recently identified somatic mutations has not been systematically evaluated ...
Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis
(2013)
Previous small series have suggested that acute myeloid leukemia with t(8;16) is a distinct morphologic and clinical entity associated with poor prognosis. We describe 18 patients with t(8;16) AML, including their clinical, ...
How do novel molecular genetic markers influence treatment decisions in acute myeloid leukemia?
(2012)
Acute myeloid leukemia (AML) is the most common acute leukemia diagnosed in adults, and the majority of patients with AML die from relapsed disease. Although many studies over the past 4 decades have identified disease ...
Effects of atropine and propranolol on lung inflammation in experimental envenomation: comparison of two buthidae venoms.
(University of Nairobi, 2013-04)
BACKGROUND:
Previous works had shown that scorpion venom induced neurotransmitter elevation and an inflammatory response associated with various anatomo-pathological modifications. The most dangerous scorpions species ...