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Now showing items 31-40 of 54
Does a voucher program improve reproductive health service delivery and access in Kenya?
(University of Nairobi, 2015)
Current assessments on Output-Based Aid (OBA) programs have paid limited attention to the experiences and perceptions of the healthcare providers and facility managers. This study examines the knowledge, attitudes, and ...
Acute-Phase Response Proteins Are Overexpressed in Vaginal Mucosa and Plasma of HIV-Resistant Women upon Viral Challenge
(University of Nairobi, 2013)
Background: The primary receptive portals of entry for HIV are
through mucosal surfaces. Our previous studies show that HIVexposed
uninfected individuals (HESN) have unique innate responses
associated with resistance ...
CD161 identifies polyfunctional Th1/Th17 cells in the genital mucosa that are depleted in HIV-infected female sex workers from Nairobi, Kenya.
(University of Nairobi, 2017)
CD161 identifies a subset of circulating Th17 cells that are depleted in the blood and gut of HIV-infected individuals. In the female reproductive tract (FRT), the pattern of CD161 expression on CD4+ cells remains unknown. ...
Association of sex work with reduced activation of the mucosal immune system
(University of Nairobi, 2014-01)
Background. Unprotected intercourse and seminal discharge are powerful activators of the mucosal immune system and are an important risk factors for HIV transmission. This study was designed to determine if female sex work ...
Effect of storage conditions on quality and aflatoxin contamination of peanuts( Arachis hypogaea L)
(University of Nairobi, 2013)
Peanuts are prone to various types of deterioration during storage which renders them unsuitable for consumption and trade resulting in large economic losses. Peanut kernels of Homabay Local, Valencia Red, ICGV-SM 12991 ...
Subtype-specific differences in gag-protease-driven replication capacity are consistent with inter-subtype differences in hiv-1 disease progression.
(University of Nairobi, 2017)
There are marked differences in the spread and prevalence of HIV-1 subtypes worldwide, and differences in clinical progression have been reported. However, the biological reasons underlying these differences are unknown. ...
Improving adherence to post-cervical biopsy sexual abstinence in kenyan female sex workers.
(University of Nairobi, 2016)
PROBLEM:
Cervical biopsies offer a unique opportunity for studying local immune response. To investigate hormonally induced immune fluctuations in cervical tissues of Kenyan female sex workers, we improved biopsy sampling ...
HIV-infected women have high numbers of CD103-CD8+ T cells residing close to the basal membrane of the ectocervical epithelium.
(University of Nairobi, 2017)
BACKGROUND:
Genital mucosa is the main portal of entry for various incoming pathogens, including HIV, hence an important site for host immune defenses. Tissue-resident memory T (TRM) cells defend tissue barriers against ...
The incidence of first-line antiretroviral treatment changes and related factors among HIV-infected sex workers in Nairobi, Kenya.
(University of Nairobi, 2017)
INTRODUCTION:
In many settings, several factors including adverse drug reactions and clinical failure can limit treatment choices for combined antiretroviral therapy (cART). The aim of the study was to describe the incidence ...
Genetic markers associated with resistance to beta-lactam and quinolone antimicrobials in non-typhoidal salmonella isolates from humans and animals in central Ethiopia.
(University of Nairobi, 2016)
INTRODUCTION:
Several risk factors including stavudine and age have been strongly associated with polyneuropathy. However, conflicting data exist on height as an independent risk factor in polyneuropathy. The objective ...