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Rapid Decline in Risk of HIV-l Acquisition After Enrollment in a Vaccine Preparedness Cohort of Kenyan Prostitutes: Implications for the Design of HIV -1 Vaccine Efficacy Trials
Background: In designing HIY-l vaccine efficacy trials, it will be important to accounrfor changes in HIY -1 incidence, especially changes over time and while participating in riskreduction programs. Methods: Data from ...
Subtypes of Human Immunodeficiency Virus Type 1 and Disease Stage among Women in Nairobi, Kenya
In sub-Saharan Africa, where the effects of human immunodeficiency virus type 1 (HIV-1) have been most devastating, there are multiple subtypes of this virus. The distribution of different subtypes within African populations ...
Correlates of human herpesvirus 8 seropositivity among heterosexual men in Kenya
Background: Several studies have suggested that sexual transmission of human herpesvirus 8 (HHV-8) occurs among homosexual men in developed countries. However, few studies have examined heterosexual HHV-8 transmission, ...
HIV-1 neutralizing activity is correlated with increased levels of chemokines in saliva of HIV-1-exposed uninfected individuals.
(University of Nairobi,, 2008)
AIM: Mucosal HIV-1 exposure stimulates a variety of mucosal immune responses, including IgA1-mediated virus neutralization, even in the absence of an established infection. We hypothesized that other immune molecules might ...