Browsing Faculty of Agriculture & Veterinary Medicine (FAg / FVM) by Author "Taracha, EL"
Now showing items 1-4 of 4
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Characterization of the fine specificity of bovine CD8 T-cell responses to defined antigens from the protozoan parasite Theileria parva
Graham, SP; Pellé, R; Yamage, M; Mwangi, DM; Honda, Y; Mwakubambanya, RS; de Villiers, EP; Abuya, E; Awino, E; Gachanja, J; Mbwika, F; Muthiani, AM; Muriuki, C; Nyanjui, JK; Onono, FO; Osaso, J; Riitho, V; Saya, RM; Ellis, SA; McKeever, DJ; MacHugh, ND; Gilbert, SC; Audonnet, JC; Morrison, WI; van der, Bruggen P; Taracha, EL (University of Nairobi.Department of Veterinary Pathology and Microbiology, University of Nairobi, Kenya., 2008-02)Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells from T. parva-immune cattle of different major histocompatibility ... -
Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle.
Akoolo, L; Pellé, R; Saya, R; Awino, E; Nyanjui, J; Taracha, EL; Kanyari, P; Mwangi, DM; Graham, SP (University of Nairobi.Department of Veterinary Pathology and Microbiology, University of Nairobi, Kenya., 2008-02)East Coast fever (ECF) is a highly fatal lymphoproliferative disease of cattle caused by Theileria parva, a tick-borne intracellular apicomplexan parasite. Parasite antigens that are targets of protective cytotoxic T ... -
Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses
Mwangi, DM; Honda, Y; Graham, SP; Pelle, R; Taracha, EL; Gachanja, J; Nyanjui, JK; Bray, J; Palmern, GH; Brown, WC; Mwagi, W (University of Nairobi.Department of Veterinary Pathology and Microbiology, University of Nairobi, Kenya., 2011-04)Theileria parva antigens recognized by cytotoxic T lymphocytes (CTLs) are prime vaccine candidates against East Coast fever in cattle. A strategy for enhancing induction of parasite-specific T cell responses by increasing ... -
Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity.
Pelle, R; Graham, SP; Njahira, MN; Osaso, J; Saya, RM; Odongo, DO; Toye, PG; Spooner, PR; Musoke, AJ; Mwangi, DM; Taracha, EL; Morrison, WI; Weir, W; Silva, JC; Bishop, RP (University of Nairobi.Department of Veterinary Pathology and Microbiology, University of Nairobi, Kenya., 2011-04)BACKGROUND: Theileria parva causes an acute fatal disease in cattle, but infections are asymptomatic in the African buffalo (Syncerus caffer). Cattle can be immunized against the parasite by infection and treatment, but ...