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Anthraquinones of the roots of Pentas micrantha
(University of Nairobi, 2012-12)
Pentas micrantha is used in the East African indigenous medicine to treat malaria. In the first investigation of this plant, the crude methanol root extract showed moderate antiplasmodial activity against the W2- (3.37 ...
Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus.
(University of Nairobi, 2012-09)
The CH2Cl2-MeOH (1:1) extract of the aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7 microg/mL) and chloroquine resistant W2 ...
Isoflavanones and 3-Methoxyflavones from the Stem Bark of Platycelphium voense
(2011)
Platycelphium (Engl.) Wild (Leguminosae) is a monotypic genus that occurs in the drier parts of
Eastern Africa (Gillett et 01., 1971). Prior to this report, the only phytochemical studies on
Platycelphium voense describe ...
A xanthone and a phenylanthraquinone from the roots of Bulbine frutescens, and the revision of six seco-anthraquinones into xanthones
(University of Nairobi, 2014)
Phytochemical investigation of the dichloromethane/methanol (1:1) extract of the roots of Bulbine frutescens led to the isolation of a new xanthone, 8-hydroxy-6-methylxanthone-1-carboxylic acid (1) and a new phenylanthraquinone, ...
Flavonoids and isoflavonoids from Tephrosia fulvinervis and Tephrosia pentaphylla
(University of Nairobi, 1989)
From the roots, leaves and pods of Tephrosia pentaphylla three new 6-oxygenated rotenoids (dihydrostemonal, 9-demethyldihydrostemonal and 6-acetoxydihydrostemonal) were isolated and characterized. In addition six known ...
Four isoflavones from seed pods of Millettia dura
(University of Nairobi, 1996-02)
Seed pods of Millettia dura yielded four novel isoflavones, which have been characterized as 3-(3,4-dimethoxyphenyl)-6-methoxy-8,8-dimethyl-4H,8H-benzo[1,2-b: 3,4-b′]dipyran-4-one (trivial name, durallone), 6-demethyldurallone, ...
Two new isoflavones from millettia dura
(2010)
The genus Millettia belongs to the family Fabaceae. It is
represented by more than 200 species and is, found widely
distributed in tropical Africa, Australia and Asia. Previous
chemical investigationsof a number" of ...
Natural Products from Plant Diversity and their Potential in Management of Neglected Diseases
(2011)
Conventionally, neglected diseases are considered as a group of 13 infectious diseases that are
. endemic in the low income populations in the tropical developing world. They can be classified
as those caused by trypanosomal ...
6-Methoxycalpogonium Isoflavone A: A New Isoflavone from the Seed Pods of Millettia dura
(University of Nairobi, 1997-08)
From the seed pods of Millettia dura a new isoflavone has been isolated and identified as 3-(4-methoxyphenyl)-6-methoxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b‘]dipyran-4-one (trivial name 6-methoxycalopogonium isoflavone A). ...