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Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum
(University of Nairobi, 2010-06)
Chromatographic separation of the roots of a Kenyan medicinal plant, Clerodendrum eriophyllum, led to the isolation of ten abietane diterpenoids (1-10), one of which (1) was isolated for the first time from a natural source. ...
Anti-plasmodial Activities Of Flavonoids From Erythrina Sacleuxii
(University of Nairobi, 2006-02)
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic ...
Flavonoids and Isoflavonoids with Antiplasmodial Activities from the Root Bark of Erythrina abyssinica
(University of Nairobi, 2003-07)
From the root bark of Erythrina abyssinica a new pterocarpene [3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene] and a new isoflav-3-ene [7,4′-dihydroxy-2′,5′-dimethoxyisoflav-3-ene] were isolated. In addition, the ...
Antiparasitic and anticancer carvotacetone derivatives from Sphaeranthus bullatus
(2012-09)
The 1:1 MeOH/CH2Cl2 extract of aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7µg/ml) and chloroquine resistant W2 (IC50 ...
Three isoflav-3-enes and a 2-arylbenzofuran from the root bark of Erythrina burttii
(University of Nairobi, 2002-02)
From the root bark of Erythrina burttii three isoflav-3-enes, 7,4′-dihydroxy-2′-methoxy-6-(1″,1″-dimethylallyl)isoflav-3-ene (trivial name, burttinol-A), 4′-hydroxy-2′-methoxy-2″,2″-dimethylpyrano[5″,6″:8,7]isoflav-3-ene ...
Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti
(University of Nairobi, 2003-10)
A crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 µg ml−1 at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera: Culicidae). The rotenoids, ...
Antimicrobial flavonoids from the stem bark of Erythrina burttii
(University of Nairobi, 2005-07)
The chloroform extract of the stem bark of Erythrina burttii showed antifungal and antibacterial activities using the disk diffusion method. Flavonoids were identified as the active principles. Activities were observed ...
Flavonoids and isoflavonoids of Erythrina burttii
(2009)
From the stem bark and root bark of Erythrina burttii twenty-three flavonoids and isoflavonoids, including some
eight new compounds, have been isolated and characterised. The stem bark of this plant mainly produces
isoflavanones ...
7a-O-methyldeguelol, a modified rotenoid with an open ring-C, from the roots of Derris trifoliata
(2005-03)
From the acetone extract of the roots of Derris trifoliata an isoflavonoid derivative, named 7a-O-methyldeguelol, a modified rotenoid with an open ring-C, representing a new sub-class of isoflavonoids (the sub-class is ...
Two isoflavanones from the stem bark of Erythrina sacleuxii
(University of Nairobi, 2000-11)
From the stem bark of Erythrina sacleuxii two new isoflavanones, (R)-5,7-dihydroxy-2′,4′,5′-trimethoxyisoflavanone (trivial name, (R)-2,3-dihydro-7-demethylrobustigenin) and (R)-5-hydroxy-2′,4′,5′-trimethoxy-2″,2″-dimeth ...