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Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum
(University of Nairobi, 2010-06)
Chromatographic separation of the roots of a Kenyan medicinal plant, Clerodendrum eriophyllum, led to the isolation of ten abietane diterpenoids (1-10), one of which (1) was isolated for the first time from a natural source. ...
Antiplasmodial activity of compounds from the surface exudates of Senecio roseiflorus
(University of Nairobi, 2013-02)
From the surface exudates of Senecio roseiflorus fourteen known methylated flavonoids and one phenol were isolated and characterized. The structures of these compounds were determined on the basis of their spectroscopic ...
Flavonoids and Isoflavonoids with Antiplasmodial Activities from the Root Bark of Erythrina abyssinica
(University of Nairobi, 2003-07)
From the root bark of Erythrina abyssinica a new pterocarpene [3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene] and a new isoflav-3-ene [7,4′-dihydroxy-2′,5′-dimethoxyisoflav-3-ene] were isolated. In addition, the ...
Antiparasitic and anticancer carvotacetone derivatives from Sphaeranthus bullatus
(2012-09)
The 1:1 MeOH/CH2Cl2 extract of aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7µg/ml) and chloroquine resistant W2 (IC50 ...
Flavonoids and isoflavonoids of Erythrina burttii
(2009)
From the stem bark and root bark of Erythrina burttii twenty-three flavonoids and isoflavonoids, including some
eight new compounds, have been isolated and characterised. The stem bark of this plant mainly produces
isoflavanones ...