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Anthraquinones of the roots of Pentas micrantha
(University of Nairobi, 2012-12)
Pentas micrantha is used in the East African indigenous medicine to treat malaria. In the first investigation of this plant, the crude methanol root extract showed moderate antiplasmodial activity against the W2- (3.37 ...
Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus.
(University of Nairobi, 2012-09)
The CH2Cl2-MeOH (1:1) extract of the aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7 microg/mL) and chloroquine resistant W2 ...
Isoflavanones and 3-Methoxyflavones from the Stem Bark of Platycelphium voense
(2011)
Platycelphium (Engl.) Wild (Leguminosae) is a monotypic genus that occurs in the drier parts of
Eastern Africa (Gillett et 01., 1971). Prior to this report, the only phytochemical studies on
Platycelphium voense describe ...
A xanthone and a phenylanthraquinone from the roots of Bulbine frutescens, and the revision of six seco-anthraquinones into xanthones
(University of Nairobi, 2014)
Phytochemical investigation of the dichloromethane/methanol (1:1) extract of the roots of Bulbine frutescens led to the isolation of a new xanthone, 8-hydroxy-6-methylxanthone-1-carboxylic acid (1) and a new phenylanthraquinone, ...
Two new isoflavones from millettia dura
(2010)
The genus Millettia belongs to the family Fabaceae. It is
represented by more than 200 species and is, found widely
distributed in tropical Africa, Australia and Asia. Previous
chemical investigationsof a number" of ...
Natural Products from Plant Diversity and their Potential in Management of Neglected Diseases
(2011)
Conventionally, neglected diseases are considered as a group of 13 infectious diseases that are
. endemic in the low income populations in the tropical developing world. They can be classified
as those caused by trypanosomal ...
Larvicidal Activities Of Extracts And Rotenoids From Millettia Usaramensis Subspecies Usaramensis On Aedes Aegypti (Linnaeus, 1762) (Diptera: Culicidae)
(University of Nairobi, 2014)
The dichloromethane/methanol (1:1) extract of the stem bark of Millettia usaramensis subspecies usaramensis was tested for its larvicidal activity against the 4th instar Aedes aegypti larvae and demonstrated activity with ...
Flemingins G–O, Cytotoxic and Antioxidant Constituents of the Leaves of Flemingia grahamiana
(2014)
The known flemingins A–C (1–3) and nine new chalcones, named flemingins G–O (4–12), along with deoxyhomoflemingin (13) and emodin (14) were isolated from a leaf extract of Flemingia grahamiana. The isolated chalcones were ...
Constituents of the Roots and Leaves of Ekebergia capensis and Their Potential Antiplasmodial and Cytotoxic Activities
(2014)
A new triterpenoid, 3-oxo-12β-hydroxy-oleanan-28,13β-olide (1), and six known triterpenoids 2–7 were isolated from the root bark of Ekebergia capensis, an African medicinal plant. A limonoid 8 and two glycoflavonoids 9–10 ...