Search
Now showing items 51-60 of 61
Terpurinflavone: An antiplasmodial flavone from the stem of Tephrosia Purpurea
(Elsevier B.V., 2011)
The stem extract of Tephrosia purpurea showed anti plasmodial activity against the D6 (chloroquinesensitive)
and W2 (chloroquine-resistant) strains of Plasmodium /aldparum with 1(50 values of
10.47 ± 2.22 f.Lg/mland 12.06 ...
Crystal Structures and Cytotoxicity ofent-Kaurane-TypeDiterpenoids from TwoAspiliaSpecies
(University of Nairobi, 2018)
A phytochemical investigation of the roots ofAspilia plurisetaled to the isolationofent-kaurane-type diterpenoids and additional phytochemicals (1–23).The structures ofthe isolated compounds were ...
A Survey Of Traditional Medicinal Uses Of Catha Edulis (Celastraceae) In Meru And Eembu Counties Of Kenya.
(University of Nairobi, 2016)
Catha edulis (qat) is an evergreen tree or shrub whose young leaves and stems are widely chewed in Eastern Africa. The
aim of the present study was to document ethnomedicinal value of Catha edulis as used traditionally ...
LC-MS-Based Metabolomics for the Chemosystematics of Kenyan Dodonaea viscosa Jacq (Sapindaceae) Populations
(University of Nairobi, 2020)
Dodonaea viscosa Jacq (Sapindaceae) is a medicinal plant with a worldwide distribution. The species has undergone enormous taxonomic changes which caused confusion amongst plant users. In Kenya, for example, two varieties ...
Antiplasmodial and antileishmanial flavonoids from Mundulea sericea
(University of Nairobi, 2020)
Five known compounds (1-5) were isolated from the extract of Mundulea sericea leaves. Similar investigation of the roots of this plant afforded an additional three known compounds (6-8). The structures were elucidated using ...
A new β-hydroxydihydrochalcone from Tephrosia uniflora, and the revision of three β-hydroxydihydrochalcones to flavanones
(University of Nairobi, 2022-04)
The CH2Cl2/MeOH (1:1) extract of the stems of Tephrosia uniflora yielded the new β-hydroxydihydrochalcone (S)-elatadihydrochalcone-2'-methyl ether (1) along with the three known compounds elongatin (2), (S)-elatadihydrochalcone ...
In Vitro Antimicrobial and Antiproliferative Activities of the Root Bark Extract and Isolated Chemical Constituents of Zanthoxylum Paracanthum Kokwaro (Rutaceae)
(University of Nairobi, 2020)
Abstract: Zanthoxylum paracanthum Kokwaro (Rutaceae) is an endemic Kenyan and Tanzanian
plant used in folk medicine by local populations. Although other Zanthoxylum species have been
studied, only Z. paracantum stem ...
Antiplasmodial and Antimicrobial Activities of Ent- Abietane Diterpenoids From the Roots of Suregada Zanzibariensis
(University of Nairobi, 2022)
The root extract ofSuregada zanzibariensisBaill. afforded six previ-ously describedent-abietane diterpenoids, namely 7-oxo-ent-abieta-5(6),8(14),13(15)-trien-16,12-olide (1), mangiolide (2),8,14b:11,12a-diepoxy ...
Benzo[ b]naphtho[2,1- d]furans and 2-Phenylnaphthalenes from Streblus usambarensis
(University of Nairobi, 2023)
Three new benzo[b]naphtho[2,1-d]furans, usambarins A-C (1-3), five new 2-phenylnaphthalenes, usambarins D-H (4-8), a new flavan (9), and a new phenyl-1-benzoxepin (10) as well as two known compounds (11 and 12) were isolated ...
A new C-C linked benzophenathridine-2-quinoline dimer, and the antiplasmodial activity of alkaloids from Zanthoxylum holstzianum
(University of Nairobi, 2023)
The CH2Cl2/MeOH (1:1) extract of Zanthoxylum holstzianum stem bark showed good antiplasmodial activity (IC50 2.5 ± 0.3 and 2.6 ± 0.3 µg/mL against the W2 and D6 strains of Plasmodium falciparum, respectively). From the ...