Browsing Faculty of Health Sciences (FHS) by Title
Now showing items 4632-4651 of 10377
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'I stayed with my illness': a grounded theory study of health seeking behaviour and treatment pathways of patients with obstetric fistula in Kenya.
(University of Nairobi, 2017)BACKGROUND: Obstetric fistula classic symptoms of faecal and urinary incontinence cause women to live with social stigma, isolation, psychological trauma and lose their source of livelihoods. There is a paucity of studies ... -
the IAVI Collaborative Seroprevalence and Incidence Study Team.Investigating the utility of the HIV-1 BED capture enzyme immunoassay using cross-se
(University of nairobiCollege of health science, 2007) -
icroRNA expression profile identifies a different signature between MYC translocation-positive and negative Burkitt Lymphoma cases
(University of Nairobi,Department Human Pathology,, 2011) -
Identification and characterization of HLA-A*0301 epitopes in HIV-1 gag proteins using a novel approach
(Department of Medical Microbiology, University of Nairobi, Nairobi, KenyaNational Microbiology Laboratory, 1015 Arlington Street, Winnipeg, Manitoba, CanadaDepartment of Medical Microbiology, University of Manitoba, 730 William Avenue, Winnipeg, Manitoba, Canada, 2010-01)Identification of CTL epitopes correlated to immune protection is important for the development of vaccines that enhance T-cell mediated immune responses. The correlation of positively selected amino acids (PS) of HIV-1 ... -
Identification And Estimation Of A Cholinomimetic Substance In The Venom Of Dendroaspis Polylepis Res. Commun. Chem. Pathol. Pharmacol.
(Department of biochemistry, university of Nairobi, 1982)A cholinomimetic substance was isolated from desiccated venom of Dendroaspis polylepis by one-dimensional ascending paper chromatography. The migratory and staining properties of the substance were compared with those of ... -
Identification and estimation of an acetylcholine-like substance in the venom of Dendroaspis jamesoni
(College of Health Sciences, University of Nairobi, 1977)An acetylcholine-like substance was isolated from desiccated Jameson's mamba venom by one-dimensional ascending paper chromatography. The migratory and staining properties of the substance were identical with those of ... -
Identification and isolation of three acetylcholinesterase inactivating fractions in the venom of Dendroaspis angusticeps.
(University of NairobiCollege of Health Sciences, 1982)Three fractions were isolated from the venom of Dendroaspis angusticeps by column chromatography on CM-Sephadex C-25. All the three fractions were shown to possess acetylcholinesterase inhibiting activity. The toxicity of ... -
Identification of a novel HLA B*57 restricted cytotoxic T-lymphocyte epitope within HIV-1 rev
(University of Nairobi,College of Health Sciences,, 2006)HLA-B5701 and its related allele B5703 have been shown to be strongly associated with slow HIV-1 disease progression. To elucidate the effect of these alleles fully on disease progression it is essential to identify key ... -
Identification of a putative structural gene for cathepsin D in Caenorhabditis elegans.
(Department of Biological Sciences, University of Pittsburgh, Pennsylvania 15260., 1988)Mutants of Caenorhabditis elegans having about 10% of wild-type activity of the aspartyl protease cathepsin D have been isolated by screening. Mutant homozygotes have normal growth rates and no obvious morphological or ... -
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Identification of antimalarial compounds from Leucas calostachys, using High Performance Liquid Chromatography and Electrospray Ionization Mass Spectrometry
(2022-09-06)Leucas calostachys is widely used in traditional medicine in Kenya for management of various ailments including malaria. Bio-assay guided fractionation of Leucas calostachys extracts was carried out using in-vitro ... -
Identification of cytokeratin 18 as a biomarker of mouse and human hepatosplenic schistosomiasis.
(University of NairobiCollege of Health Science, 2011-02)Previously, we demonstrated unique protein expression patterns in 20-week-Schistosoma mansoni-infected CBA/J mice with moderate splenomegaly syndrome (MSS) or hypersplemomegaly syndrome (HSS). To better understand the ... -
Identification of DHBcAg as a potent carrier protein comparable to KLH for augmenting MUC1 antigenicity
(University of NairobiSchool of Public Health, University of Nairobi, 2005-09)MUC1 is expressed at the cell surface of epithelial cancers. We have shown previously that MUC1 conjugated to keyhole limpet hemocyanin (KLH) plus the saponin immunological adjuvant QS-21 induces consistent high titer IgM ... -
Identification of DNA marker specific to medium-sized chromosome 4 of Trypanosoma congolense
(Department of Biochemistry, University of Nairobi, 2004)Genomic DNA from T. congolense clone I~1180 was purified and resolved by pulsed field gradient gel electrophoresis (PFGE) technique to separate the genome into chromosome-sized DNA molecules. PFGE conditions most ideal for ... -
Identification of DNA markers specific to medium-sized chromosomes 4 of Trypanosoma congolense
(Intemational Livestock Research InstituteDepartment of Biochemistry, University of Nairobi, 2004)Genomic DNA from T. congolense clone I~1180 was purified and resolved by pulsed field gradient gel electrophoresis (PFGE) technique to separate the genome into chromosome-sized DNA molecules. PFGE conditions most ideal for ... -
Identification Of Four Novel Kir2dl2 Alleles And Two Novel Kir2dl3 Alleles In An East African Population.
(University of NairobiDepartment of Medical Microbiology, 2010-12)We report four novel KIR2DL2 alleles and two novel KIR2DL3 alleles identified from an East African population using sequence-based typing. Sequencing and molecular cloning of exon 4 confirmed that the new 2DL2 alleles were ... -
Identification of Glycosyl Hydrolase producing Extremophilic bacterium using ribosomal DNA sequence. Sequence deposited at Gene Bank under accession number
(University of NairobiDepartment of Biochemistry, 2006) -
Identification of malaria transmission and epidemic hotspots in the western kenya highlands
(College of Health Sciences, University of Nairobi, 2011)Background: Malaria in the western Kenya highlands is characterized by unstable and high transmission variability which results in epidemics during periods of suitable climatic conditions. The sensitivity of a site to ... -
Identification of modifiable factors that affect the genetic diversity of the transmitted HIV-1 population
(Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington,Department of Medical Microbiology, University of Nairobi, 2004)BACKGROUND: Our previous studies have shown that the majority of African women were infected with multiple HIV-1 genetic variants, while in the remaining women only a single viral genotype was detected early in infection. ... -
Identification of novel erythromycin derivatives in mother liquor concentrates of streptomyces erythraeus
(1987)The identification of five novel compounds, pseudo-erythromycin A-6,9-hemiketal, 8,9- anhydro-pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-N-demethylerythromycin A-6,9-hemiketal, 5-0-fl-o-desosaminylerythronolide ...
