Browsing Faculty of Health Sciences (FHS) by Author "Zatyka, Malgorzata"
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Identification Of Novel VHL Target Genes And Relationship To Hypoxic Response Pathways.
Maina, Esther N; Morris, Mark R; Zatyka, Malgorzata; Raval, Raju R; Banks, Rosamonde E; Richards, Frances M; Johnson, Claire M; Maher, Eamonn R (Department of Biochemistry, 2005)Upregulation of hypoxia-inducible factors HIF-1 and HIF-2 is frequent in human cancers and may result from tissue hypoxia or genetic mechanisms, in particular the inactivation of the von Hippel–Lindau (VHL) tumour suppressor ...