Browsing Faculty of Health Sciences (FHS) by Author "[et al.]"
Now showing items 1-16 of 16
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Effectiveness of hormonal contraception in HIV-infected women using antiretroviral therapy.
Pyra, M; Heffron, R; Mugo, NR; Nanda, K; Thomas, KK; Celum, C; Kourtis, AP; Were, E; [et al.] (University of Nairobi, 2015)OBJECTIVE: The objective of this study is to assess whether antiretroviral therapy (ART) may diminish the effectiveness of hormonal contraceptive methods. METHODS: Using data from 5153 HIV-infected women followed ... -
Enabling the development and deployment of next generation point-of-care diagnostics
Derda, Ratmir; Gitaka, J; Klapperich, CM; Mace, CR; Kumar, AA; Lieberman, M; [et al.] (University of Nairobi, 2015-05-14) -
Gender differences in treatment outcomes among 15-49 year olds with smear-positive pulmonary tuberculosis in Kenya
Kosgei, RJ; Sitienei, JK; Kipruto, H; Kimenye, K; Gathara, D; Odawa, FX; Gichangi, P; Callens, S; [et al.] (University of Nairobi, 2015)OBJECTIVE: To determine gender differences in treatment outcomes among 15-49 year olds with smear-positive pulmonary tuberculosis (PTB) and factors associated with poor outcomes in Kenya. DESIGN: Retrospective ... -
Genomic epidemiology of the current wave of artemisinin resistant malaria
Amato, R; Miotto, O; Woodrow, C; Almagro-Garcia, J; Sinha, I; Campino, S; Mead, D; Drury, E; [et al.] (University of Nairobi, 2015)Artemisinin resistant Plasmodium falciparum is advancing across Southeast Asia in a soft selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, we find that kelch13 mutations which ... -
Host Genetic and Viral Determinants of HIV-1 RNA Set Point among HIV-1 Seroconverters from Sub-Saharan Africa
Mackelprang, Romel D.; Carrington, Mary; Thomas, Katherine K; Hughes, James P.; Jared, M. Baeten; Wald, Anna; Farquha, Carey; Fife, Kenneth; [et al.] (University of Nairobi, 2015-09-03)ABSTRACT We quantified the collective impact of source partner HIV-1 RNA levels, human leukocyte antigen (HLA) alleles, and innate re- sponses through Toll-like receptor (TLR) alleles on the HIV-1 set point. Data came ... -
How do clinicians prefer cultural competence training? Findings from the DSM-5 cultural formulation interview field trial.
Aggarwal, NK; Lam, P; Castillo, EG; Weiss, MG; Diaz, E; Alarcón, RD; van Dijk, R; Rohlof, H; Ndetei, DM; [et al.] (University of Nairobi, 2015-10)OBJECTIVE: This study's objective is to analyze training methods clinicians reported as most and least helpful during the DSM-5 Cultural Formulation Interview field trial, reasons why, and associations between demographic ... -
Identification of antimalarial compounds from Leucas calostachys, using High Performance Liquid Chromatography and Electrospray Ionization Mass Spectrometry
Mukungu, N. A; Okalebo, F. A.; Abuga, K. O; Oyugi, J. O.; Ochola, L.; Tanabe, M.; Mwangi, J. W; [et al.] (2022-09-06)Leucas calostachys is widely used in traditional medicine in Kenya for management of various ailments including malaria. Bio-assay guided fractionation of Leucas calostachys extracts was carried out using in-vitro ... -
Knowledge, Attitude and Practices of health care workers on corticosteroid adverse drug events in rheumatologic, respiratory and dermatologic clinics in a teaching hospital in Nairobi
Ilovi, CS; Mecha, JO; Kigamwa, P; Mutai, K; Mwachinga, M; Genga, EK; Sheikh, A; Owino, B; [et al.] (University of Nairobi, 2015-06)Background: Corticosteroids form the cornerstone of management for a myriad of rheumatological, dermatological and chronic respiratory tract diseases. Whereas these drugs are crucial in reducing morbidity and ... -
Molecular signatures of immune activation and epithelial barrier remodeling are enhanced during the luteal phase of the menstrual cycle: implications for HIV susceptibility
Birse, Kenzie; Arnold, Kelly B.; Novak, Richard M.; McCorrister, Stuart; Shaw, Souradet; Westmacott, Garrett R.; Ball, Terry B.; Lauffenburger, Douglas A.; [et al.] (University of Nairobi, 2015)Variable infectivity and transmissibility of HIV/SHIV has been recently associated with the menstrual cycle, with particular susceptibility observed during the luteal phase in non-human primate models and ex vivo human ... -
Neonatal Ebstein’s Anomaly: Surgical Decision Making
Awori, M; Mutwiri, R. K; Mutunga, W. M; [et al.] (Annals of African Surgery, 2018-01)Ebstein’s Anomaly (EA) is a rare form of congenital heart disease. Surgical decision-making in neonates is controversial. In developing countries, neonates with Ebstein’s anomaly requiring surgical intervention rarely ... -
New pneumococcal conjugate vaccine introductions in four sub-Saharan African countries: a cross-country analysis of health systems’ impacts
Torres-Rueda, Sergio; urchett; Burchett, Helen ED; Griffiths, Ulla K; Ongolo-Zogo, Pierre; Edengue, Jean-Marie; Kitaw, Yayehyirad; Molla, Mitike; Gelmon, Lawrence; Onyango-Ouma, Washington; [et al.] (University of Nairobi, 2015-09)Background: Pneumonia is a main cause of under-five mortality in low-income settings. The pneumococcal conjugate vaccine (PCV) has been introduced in many countries as a tool in the disease’s prevention. Although PCV’s ... -
Outcome of Gunshot Abdominal Injuries
Bonko, N.M.; Badawy, Maryam; Nchifor, K; Mumba, M; [et al.] (ANNALS of AFRICAN SURGERY, 2020-02-05)Aim: To describe prevalence, management and factors determining outcomes in patients presenting with gunshot abdominal injuries. Method: We retrospectively analysed all cases of gunshot to the abdomen received at Kenyatta ... -
Outcome of the first medicines utilization research in Africa group meeting to promote sustainable and rational medicine use in Africa.
Massele, A; Burger, J; Katende-Kyenda, NL,; Kalemeera, F; Kenaope, T; Kibuule, D,; Mbachu, O,; Mubita, M; [et al.] (University of Nairobi, 2015)The second Medicines Utilization Research in Africa (MURIA) group workshop and symposium again brought researchers together from across Africa to improve their knowledge of drug utilization (DU) methodologies and exchange ... -
Safety and efficacy of antenatal iron supplementation in a malaria-endemic area in Kenya: A randomised trial
Mwangi, Martin N; Roth, Johanna M; Smit, Menno; Trijsburg, Laura; Mwangi, Alice; Demir, Ayşe Y; Mens, Petra; Prentice, Andrew M; [et al.] (University of Nairobi, 2015)Objectives: Whereas coverage of antenatal iron supplementation is low and benefits are uncertain, there are concerns that it can increase the burden of malaria, with potentially devastating effects on maternal and neonatal ... -
Topic: Inguinal Hernia - Influence of guidelines on daily practice.
Zanella, S; Vassiliadis, A; Buccelleti, F; Ricci, F; Verma, S; Bali, RS; Agarwal, PN; Singh, R; [et al.] (University of Nairobi, 2015-04) -
Virus-encoded microRNA contributes to the molecular profile of EBV-positive burkitt lymphomas.
Piccaluga, PP; Navari, M; Falco, G; Ambrosio, MR; Lazzi, S; Fuligni, F; Bellan, C; Rossi, M; [et al.] (University of Nairobi, 2015-07)Burkitt lymphoma (BL) is an aggressive neoplasm characterized by consistent morphology and phenotype, typical clinical behavior and distinctive molecular profile. The latter is mostly driven by the MYC over-expression ...