Resistance to the antifolate sulfadoxine–pyrimethamine (SP), the current mass-treatment antimalarial drug, is associated with selection of point mutations in dihydrofolate reductase and dihydropteroate synthase. Among these ...

Recent evidence demonstrates interactions between malaria and HIV infection. HIV-infected people are more likely to experience clinical malaria, and acute malaria can up-regulate HIV replication, leading to higher plasma ...

Erythrocyte surface proteins have been identified as receptors of Plasmodium falciparum merozoite proteins. The ligand-receptor interactions enable the parasite to invade human erythrocytes, initiating the clinical symptoms ...

Large-scale studies of genomic variation could assist efforts to eliminate malaria. But there are scientific, ethical and practical challenges to carrying out such studies in developing countries, where the burden of disease ...

A study was carried out to determine the range of antimalarial drugs stocked and also to determine the knowledge and practice patterns of shopkeepers and their customers on antimalarial products stocked and bought. It was ...

The Blantyre coma scale (BCS) is used to assess children with severe falciparum malaria, particularly as a criterion for cerebral malaria, but it has not been formally validated. We compared the BCS to the Adelaide coma ...

A study on the comparative efficacy of two antimalarial drugs, namely chloroquine and sulfadoxine/pyrimethamine combination in the treatment of falciparum malaria was carried out in Siaya District, Nyanza Province of Kenya. ...

Nefang is a polyherbal preparation constituted of the leavesof six plants and the bark of one of these,used traditionally for the treatment of malaria by the Bayang community, South West Region of Cameroon. Since ...