Now showing items 1-10 of 22
Prolapsed Inter-vertebral disc in an African population
Characteristics of Prolapsed Intervertebral Disc (PID) in Africa, reports are scanty and often disparate PID in Kenya is commonest in the lower lumbar region of young people more in females and is associated with trauma
CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa
Background: Clinical laboratory reference intervals have not been established in many African countries, and non-local intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African ...
Circumcision preference among women and uncircumcised men prior to scale-up of male circumcision for HIV prevention in Kisumu, Kenya
Following the endorsement by the World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS) of male circumcision as an additional strategy to HIV prevention, initiatives to introduce safe, ...
HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers
Objectives: Most HIV-1 transmission is sexual; therefore, immune responses in the genital mucosa may be important in mediating protection against HIV infection. This study examined HIV-1-specific mucosal IgA in a cohort ...
Does prospective monitoring improve cataract surgery outcomes in Africa?
Aims: To determine if prospective monitoring influences cataract surgical outcomes in east Africa. Methods: A prospective observational study of all routine extracapsular cataract extractions with posterior chamber lens ...
Population pharmacokinetics of a single daily intramuscular dose of gentamicin in children with severe malnutrition
The World Health Organization recommends that all children admitted with severe malnutrition should routinely receive parenteral ampicillin and gentamicin; despite this, mortality remains high. Since this population group ...
The place of knowledge management in influencing lasting health change in Africa: an analysis of AMREF's progress.
(University of Nairobi, 2012)
INTRODUCTION: AMREF (African Medical and Research Foundation) developed a Knowledge Management Strategy that focused on creating, capturing and applying health knowledge to close the gap between communities and health ...
Prevention of mother-to-child transmission of HIV-1 in Africa.
PIP: With the prevalence of HIV among pregnant women higher than 35% in some parts of sub-Saharan Africa, the number of HIV-infected children will continue to grow. It is estimated that almost 70% of the approximately ...
Breast milk HIV-1 suppression and decreased transmission: a randomized trial comparing HIVNET012 nevirapine versus short-course zidovudine
Objective: To compare the effect of perinatal regimens of short-course nevirapine (HIVNET012)andzidovudine[Thai-CentersforDiseaseControlandPrevention(CDC) regimen] on breast milk viral shedding and perinatal transmission ...
Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?
Resistance to the antifolate sulfadoxine–pyrimethamine (SP), the current mass-treatment antimalarial drug, is associated with selection of point mutations in dihydrofolate reductase and dihydropteroate synthase. Among these ...