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Now showing items 1-10 of 10
Viral linkage in HIV-1 seroconverters and their partners in an HIV-1 prevention clinical trial.
(Univesity of Nairobi, 2011-03)
BACKGROUND:
Characterization of viruses in HIV-1 transmission pairs will help identify biological determinants of infectiousness and evaluate candidate interventions to reduce transmission. Although HIV-1 sequencing is ...
Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.
(Univesity of Nairobi, 2010)
Unreported antiretroviral use by HIV-1-infected participants enrolling in a prospective research study.
(University of Nairobi, 2014-02)
Toll-like receptor gene variants and bacterial vaginosis among HIV-1 infected and uninfected African women.
(University of Nairobi, 2015)
Bacterial vaginosis (BV) is a common vaginal syndrome associated with altered microflora that increases the risk of preterm delivery and acquisition of sexually transmitted diseases. The cause of BV is unknown although ...
Genital HIV-1 RNA predicts risk of heterosexual HIV-1 transmission.
(Univesity of Nairobi, 2011-04)
High plasma HIV-1 RNA concentrations are associated with an increased risk of HIV-1 transmission. Although plasma and genital HIV-1 RNA concentrations are correlated, no study has evaluated the relationship between genital ...
Increased risk of HIV-1 transmission in pregnancy: a prospective study among African HIV-1-serodiscordant couples.
(Univesity of Nairobi, 2011-09)
Physiologic and behavioral changes during pregnancy may alter HIV-1 susceptibility and infectiousness. Prospective studies exploring pregnancy and HIV-1 acquisition risk in women have found inconsistent results. No study ...
Increased risk of HIV-1 transmission in pregnancy: a prospective study among African HIV-1-serodiscordant couples.
(2011)
Physiologic and behavioral changes during pregnancy may alter HIV-1 susceptibility and infectiousness. Prospective studies exploring pregnancy and HIV-1 acquisition risk in women have found inconsistent results. No study ...
Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.
(2010)
Most persons who are infected with human immunodeficiency virus type 1 (HIV-1) are also infected with herpes simplex virus type 2 (HSV-2), which is frequently reactivated and is associated with increased plasma and genital ...
Estimating the impact of plasma HIV-1 RNA reductions on heterosexual HIV-1 transmission risk.
(Univesity of Nairobi, 2010-09)
BACKGROUND:
The risk of sexual transmission of HIV-1 is strongly associated with the level of HIV-1 RNA in plasma making reduction in HIV-1 plasma levels an important target for HIV-1 prevention interventions. A ...
Daily Acyclovir to Decrease Herpes Simplex Virus Type 2 (HSV-2) Transmission from HSV-2/HIV-1 Coinfected Persons: A Randomized Controlled Trial.
(University of Nairobi, 2013)
Background. Daily suppressive therapy with valacyclovir reduces risk of sexual transmission of herpes simplex virus type 2 (HSV-2) in HSV-2-serodiscordant heterosexual couples by 48%. Whether suppressive therapy reduces ...