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Family connectedness and its association with sexual risk-taking among undergraduate students at the University of Nairobi
(East African Health Research commission, 2019)
Background: Universities have a student population in the age range of 17 to 25 years, 75 % of whom are sexually active, with the median age of sexual debut at age 18 years. About half of all students are involved in risky ...
Health promotion at the workplace setting: a protocol for a systematic review of effectiveness and sustainability of current practice in low-income and middle-income countries.
(University of Nairobi, 2019)
INTRODUCTION:
Low-income and middle-income countries (LMICs) are experiencing a growing disease burden due to non-communicable diseases (NCDs). Changing behavioural practices, such as diets high in saturated fat, salt ...
Noncommunicable disease burden among HIV patients in care: a national retrospective longitudinal analysis of HIV-treatment outcomes in Kenya, 2003-2013.
(BMC, 2019-04-03)
Over the last decade, the Kenyan HIV treatment program has grown exponentially, with improved survival among people living with HIV (PLHIV). In the same period, noncommunicable diseases (NCDs) have become a leading contributor ...
HIV-1 viral control varies by viral subtype in a large cohort of African adults with incident HIV-1 infection.
(Oxford Academic, 2019-04-02)
Few HIV-infected persons can maintain low viral levels without therapeutic intervention. We evaluate predictors of spontaneous viral control in a prospective cohort of African adults shortly after HIV infection. Viral ...
Live attenuated varicella-zoster virus vaccine does not induce HIV target cell activation.
(BMC, 2019-02-01)
BACKGROUND:
Varicella-zoster virus (VZV) is under consideration as a promising recombinant viral vector to deliver foreign antigens including HIV. However, new vectors have come under increased scrutiny, since trials with ...
Plasmid profiling and incompatibility grouping of multidrug resistant Salmonella enterica serovar Typhi isolates in Nairobi, Kenya.
(University of Nairobi, 2019)
OBJECTIVES:
Plasmids harbour antibiotic resistance genes which contribute to the emergence of multidrug resistant pathogens. We detected the presence of plasmids in multidrug resistant Salmonella enterica serovar Typhi ...
A grounded theory of regaining normalcy and reintegration of women with obstetric fistula in Kenya.
(University of Nairobi, 2019)
BACKGROUND:
Obstetric fistula is a reproductive health problem causing immense suffering to 1% of women in Kenya that is formed as sequelae of prolonged obstructed labour. It is a chronic illness that disrupts women ...
gyrA and parC mutations in fluoroquinolone-resistant Neisseria gonorrhoeae isolates from Kenya.
(BMC, 2019-04-08)
Phenotypic fluoroquinolone resistance was first reported in Western Kenya in 2009 and later in Coastal Kenya and Nairobi. Until recently gonococcal fluoroquinolone resistance mechanisms in Kenya had not been elucidated. ...
Few Plasmodium falciparum merozoite ligand and erythrocyte receptor pairs show evidence of balancing selection
(Elsevier, 2019-04)
Erythrocyte surface proteins have been identified as receptors of Plasmodium falciparum merozoite proteins. The ligand-receptor interactions enable the parasite to invade human erythrocytes, initiating the clinical symptoms ...
Supporting the Management of Patients with Heart Failure within Asia-Pacific, Middle East, and African Countries: A Toolbox for Healthcare Providers.
(Karger, 2019-04-04)
OBJECTIVES:
The management of heart failure (HF) is most effective when established treatment guidelines and recommendations are followed. We aimed to develop a "Toolbox" of resources to facilitate the care of patients ...