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Live Attenuated Zoster Vaccine Boosts Varicella Zoster Virus (VZV)-Specific Humoral Responses Systemically and at the Cervicovaginal Mucosa of Kenyan VZV-Seropositive Women.
(Oxford Academic, 2018-09-08)
BACKGROUND:
Attenuated varicella zoster virus (VZV) is a promising vector for recombinant vaccines. Because human immunodeficiencyvirus (HIV) vaccines are believed to require mucosal immunogenicity, we characterized mucosal ...
Caregiver oral rehydration solution fluid monitoring charts versus standard care for the management of some dehydration among Kenyan children: a randomized controlled trial.
(University of Nairobi, 2018)
Background:
Diarrhoea is a major cause of child mortality. Although oral rehydration solution (ORS) is an efficacious intervention for correcting dehydration, inadequate monitoring may limit its effectiveness in routine ...
The history of the formation of the Pan African paediatric surgical Association (PAPSA).
(University of Nairobi, 2018)
Political change in the 1990s in Southern Africa influenced the long awaited formation of a children's surgical association in Africa. Here, within is the historical account of the formation of the Pan African Association ...
Global Distribution of Human Protoparvoviruses
(BMC, 2018-07-07)
Development of next-generation sequencing and metagenomics has revolutionized detection of novel viruses. Among these viruses are 3 human protoparvoviruses: bufavirus, tusavirus, and cutavirus. These viruses have been ...
Multidimensional needs of patients living and dying with heart failure in Kenya: a serial interview study.
(University of Nairobi, 2018)
BACKGROUND:
Heart failure is an emerging challenge for Sub Saharan Africa. However, research on patients' needs and experiences of care is scarce with little evidence available to support and develop services. We aimed ...
Coexistence of gout and rheumatoid arthritis in Nairobi, Kenya
(University of Nairobi, 2018)
Background: There is a widespread
belief that gout and RA rarely coexist in
the same patient. Given that there is an
excess burden of cardiovascular disease
in patients with RA, this is compounded
by hyperuricemia. ...
Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study.
(Elsevier, 2018-04-21)
BACKGROUND:
There is a need to increase access to surgical treatments in African countries, but perioperative complications represent a major global health-care burden. There are few studies describing surgical outcomes ...
Trends, treatment outcomes, and determinants for attrition among adult patients in care at a large tertiary HIV clinic in Nairobi, Kenya: a 2004-2015 retrospective cohort study.
(2018-06-29)
BACKGROUND:
Understanding trends in patient profiles and identifying predictors for adverse outcomes are key to improving the effectiveness of HIV care and treatment programs. Previous work in Kenya has documented findings ...
Prevalence and predictors of physical inactivity levels among Kenyan adults (18-69 years): an analysis of STEPS survey 2015.
(BMC, 2018-11-07)
BACKGROUND:
Physical inactivity accounts for more than 3 million deaths worldwide, and is implicated in causing 6% of coronary heart diseases, 7% of diabetes, and 10% of colon or breast cancer. Globally, research has shown ...
Improving Access to Cancer Testing and Treatment in Kenya.
(2018-09-04)
PURPOSE:
In response to the increasing cancer burden in Kenya, this study identified barriers to patients seeking access to cancer testing and treatment and to clinicians in delivering these services. Policy recommendations ...