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Optimizing paediatric HIV care in Kenya: challenges in early infant diagnosis
(University of Nairobi., 2008-02)
PROBLEM:
In 2003, the goal of the Kenyan Ministry of Health was to avail antiretroviral treatment (ART) to 50% of the estimated 250 000 eligible individuals by the end of 2005. By July 2005, 45 000 adults and more than ...
Acute HIV infection among Kenyan infants.
(University of Nairobi., 2008-01)
BACKGROUND:
Clinical signs and symptoms of acute human immunodeficiency virus (HIV) infection in infants are not well characterized.
METHODS:
Serial clinical assessments and HIV PCR assays were conducted in a cohort of ...
Correlates of mother-to-child human immunodeficiency virus type 1 (HIV-1) transmission: association with maternal plasma HIV-1 RNA load, genital HIV-1 DNA shedding, and breast infections
(2001)
To determine the effects of plasma, genital, and breast milk human immunodeficiency virus type 1 (HIV-1) and breast infections on perinatal HIV-1 transmission, a nested case-control study was conducted within a randomized ...
Comparison of CD4 Cell Count, Viral Load, and other markers for the prediction of mortality among HIV-1–Infected Kenyan pregnant women
(2009)
Background. There are limited data regarding the relative merits of biomarkers as predictors of mortality or time
to initiation of antiretroviral therapy (ART).
Methods. We evaluated the usefulness of the CD4 cell count, ...
Infants with late breast milk acquisition of HIV-1 generate interferon-gamma responses more rapidly than infants with early peripartum acquisition
(2009)
Infants infected with HIV-1 after the first month of life have a lower viral
set-point and slower disease progression than infants infected before 1
month. We investigated the kinetics of HIV-1-specific CD8+ T ...
Partner notification by HIV-1 seropositive pregnant women: association with infant feeding decisions
(2001-04)
Each year, an estimated 600 000 perinatal HIV-1 infections occur despite the availability of interventions to decrease mother-to-child transmission of HIV-1 [1]. In order to implement perinatal HIV-1 interventions it is ...
Longitudinal analysis of human immunodeficiency virus type 1 RNA in breast milk and of its relationship to infant infection and maternal disease
(2003-03)
Transmission of human immunodeficiency virus type 1 (HIV-1) via breast-feeding can occur throughout lactation. Defining both fluctuation in breast-milk virus level over time and how breast-milk virus correlates with ...
Infant Feeding Practices of Women in a Perinatal HIV-1 Prevention Study in Nairobi, Kenya
(2004)
Objective: To determine feeding practices and nutritional status of
infantsborntoHIV-1–infectedwomen.
Methods: Feeding plans and practices were evaluated by questionnaires
and focus group discussions. Infants were weighed ...