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Now showing items 61-70 of 233
Hormonal contraception, vitamin A deficiency, and other risk factors for shedding of HIV-1 infected cells from the cervix and vagina.
(University of Nairobi, 1997-09)
BACKGROUND: Factors that influence shedding of HIV-1 infected cells in cervical and vaginal secretions may be important determinants of sexual and vertical transmission of the virus. We investigated whether hormonal ...
The role of cytotoxic T-cells in HIV infection
(University of Nairobi, 1998)
HIV-specific cytotoxic T lymphocytes (CTL) are believed to play a major role in controlling virus levels through the asymptomatic period of HIV infection. For the rational design of an HIV vaccine, we need to know whether ...
Increased risk of genital ulcer disease in women during the first month after initiating antiretroviral therapy
Genital ulcer disease (GUD) is common in HIV-1-infected women, and a small number of stu dies have suggested increased GUD risk after antiretroviral therapy (ART) initiation. To better define this risk, we monitored 134 ...
Mother-child class I HLA concordance increases perinatal human immunodeficiency virus type 1 transmission
(University of Nairobi, 1998-03)
Major histocompatibility complex (MHC) gene products are expressed on human immunodeficiency virus (HIV)-infected cells and incorporated into the lipid envelope of HIV virions. Macaques immunized with human MHC gene products ...
Clinical and in situ cellular responses to Haemophilus ducreyi in the presence or absence of HIV infection.
(1998)
We aimed to determine if the clinical and histological features of chancroid are altered by HIV infection. Male patients presenting to the Nairobi special treatment clinic with a clinical diagnosis of chancroid were eligible ...
HIV-1 and immunological changes during pregnancy: a comparison between HIV-1-seropositive and HIV-1-seronegative women in Nairobi, Kenya.
(University of Nairobi, 1995-09-09)
OBJECTIVE:
To assess changes in the proportion of CD4 and CD8 T-lymphocyte profiles during pregnancy, at delivery and postpartum, and to determine whether HIV-1 infection affects the normal profile.
DESIGN AND METHODS:
A ...
Field testing of Modified Bieling Media for the Isolation of H. ducreyi in Kenya
(University of Nairobi, 1987)
Prospective Study Of Hormonal Contraceptive Use And Cervical Shedding Of Herpes Simplex Virus In Human Immunodeficiency Virus Type 1-seropositiv
(University of Nairobi, 2002-06)
Cross-sectional analyses have demonstrated an association between use of hormonal contraceptives and shedding of herpes simplex virus (HSV). This prospective study evaluated the effect of initiating use of hormonal ...
Plummer Fa.HLA-A and HLA-B In Kenya, Africa: Allele Frequencies And Identification Of HLA- B*1567 And HLA- B*4426. Tissue Antigens.
(University of Nairobi, 2002-05)
HLA-A and HLA-B alleles of a population from Kenya, Africa were examined by sequencing exon 2 and exon 3 DNA and typing using a Taxonomy-based Sequence-analysis (TBSA) method. Extensive diversities were observed at both ...
Association Between Cervical Shedding Of Herpes Simplex Virus And Hiv-1.aids
(University of Nairobi, 2002-12-06)
OBJECTIVE: To investigate the association between the cervical shedding of herpes simplex virus (HSV) and HIV-1. DESIGN: A cross-sectional study on 200 women seropositive for both HSV-2 and HIV-1 was conducted in a family ...