Now showing items 1-10 of 16
Loss to Follow-Up as a Competing Risk in an Observational Study of HIV-1 Incidence
OBJECTIVE: Conventional survival estimates may be biased if loss to follow-up (LTF) is associated with the outcome of interest. Our goal was to assess whether the association between sexual risk behavior and HIV-1 ...
Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells throughout the menstrual cycle
(University of Nairobi, 1998-10)
Cervical and vaginal secretions from 17 women infected with human immunodeficiency virus type 1 (HIV-1) were evaluated daily through the course of one menstrual cycle for HIV-1 DNA (21-31 visits per woman). HIV-1-infected ...
Association Between Cervical Shedding Of Herpes Simplex Virus And Hiv-1.aids
(University of Nairobi, 2002-12-06)
OBJECTIVE: To investigate the association between the cervical shedding of herpes simplex virus (HSV) and HIV-1. DESIGN: A cross-sectional study on 200 women seropositive for both HSV-2 and HIV-1 was conducted in a family ...
Hormonal Contraception And Risk Of Cervical Infections Among Hiv-1-seropositive Kenyan Women
(University of Nairobi, 2004-11-05)
Cervical Shedding Of Cytomegalovirus In Human Immunodeficiency Virus Type 1-infected Women.
(University of Nairobi, 1999)
Cervical shedding of cytomegalovirus (CMV) is important in transmission of CMV to exposed sexual partners and neonates. We evaluated prevalence and correlates of CMV DNA shedding in cervical secretions from a large cohort ...
Treatment Of Cervicitis Is Associated With Decreased Cervical Shedding Of Hiv-1. AIDS
OBJECTIVE: To determine whether cervical mucosal shedding of HIV-1 RNA and HIV-1 infected cells decreases following successful treatment of cervicitis. DESIGN: Prospective interventional study. SETTING: Sexually Transmitted ...
Phylogenetic evaluation of Kenyan HIV type 1 isolates.AIDS Res Hum Retroviruses
(University of Nairobi, 1997-04)
Diversity among global isolates of HIV-1 presents a formidable challenge for vaccine development. As distinct clades of the virus are recognized, it will be important to monitor their geographic distribution and divergence. ...
The Effect Of Hormonal Contraception On Genital Tract Shedding Of Hiv-1.aids
(University of Nairobi, 2004-01-23)
OBJECTIVE: A previous cross-sectional study reported that hormonal contraception may be associated with increased infectivity in HIV-1 infected women. We conducted a prospective study to determine if cervical shedding of ...
A Prospective Study Of Risk Factors For Herpes Simplex Virus Type 2 Acquisition Among High-risk Hiv-1 Seronegative Women In Kenya
(University of Nairobi, 2009)
Objectives: Several studies have demonstrated an association between herpes simplex virus type 2 (HSV-2) and HIV-1, but available data on risk factors for HSV-2 acquisition are limited. The objective of this analysis was ...
Identification of modifiable factors that affect the genetic diversity of the transmitted HIV-1 population
BACKGROUND: Our previous studies have shown that the majority of African women were infected with multiple HIV-1 genetic variants, while in the remaining women only a single viral genotype was detected early in infection. ...