Background: Clinical laboratory reference intervals have not been established in many African countries, and non-local intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African ...

Aims: To determine if prospective monitoring influences cataract surgical outcomes in east Africa. Methods: A prospective observational study of all routine extracapsular cataract extractions with posterior chamber lens ...

The World Health Organization recommends that all children admitted with severe malnutrition should routinely receive parenteral ampicillin and gentamicin; despite this, mortality remains high. Since this population group ...

Objective: To compare the effect of perinatal regimens of short-course nevirapine (HIVNET012)andzidovudine[Thai-CentersforDiseaseControlandPrevention(CDC) regimen] on breast milk viral shedding and perinatal transmission ...

Resistance to the antifolate sulfadoxine–pyrimethamine (SP), the current mass-treatment antimalarial drug, is associated with selection of point mutations in dihydrofolate reductase and dihydropteroate synthase. Among these ...

Objectives Todeterminetheprevalenceof life-timedomesticviolencebythecurrent partnerbeforeHIV-1testing,itsimpactontheuptakeofpreventionofmother-to-child transmission (PMTCT) interventions and frequency after testing. Design ...

A multinational injury surveillance pilot project was carried out in five African countries in the first half of 2007 (Democratic Republic of the Congo, Kenya, Nigeria, Uganda and Zambia). Hospitals were selected in each ...

Objective We examined whether HIV-1 testing using a rapid assay increases the proportion of pregnant women obtaining HIV-1 results and the uptake of perinatal HIV-1 interventions. Methods Pregnant women attending ...

Background: Accurate predictions of HIV-I incidence in potential study populations are essential for designing HIV-I vaccine efficacy trials. Lillie information is available on the estimated incidence of HIV-I in such ...