Renal Osteodystrophy As Seen At Kenyatta National Hospital

Abstract

31 patients (17 males and 14 females) were studied Clinical renal osteodystrophy, taken as bone tenderness with restricted joint movements, was found in 21(67.7%) patients and there was no difference between the two sexes. Clinical renal osteodystrophy was found among all the ago groups studied (15 to 50 years)® Pain in the lumbar and long bones were a-RTong the most frequent and consistent early complaint^. Serial skeletal x-rays r_taken-, were all reported normal. The mean duration of illness of patients with clinical renal osteodystrophy was 36.5 ± 13»9 months and this was

found to be significant (.O1^P< .025). Biochemical renal osteodystrophy, taken as raised sei'um alkaline r phosphatase (mean 182.4 + 39*1 mmo1/1) and serum inorganic phosphate (mean 3*36 ± 1.25tnmol/l) , was found in l8 (58.1?o) of 31 patients. There was significant correlation between creatinine clearance (mean 10.29± 15.1ml/min) and biochemical renal osteodystrophy (P .01) .