Browsing Faculty of Health Sciences (FHS) by Author "Karanja, SM"
Now showing items 1-1 of 1
-
Preclinical drug evaluation system in the Plasmodium knowlesi baboon model of malaria: the methotrexate study
Kokwaro, G; Ichagichu, M; Ngotho, M; Karanja, SM; Kariuki, T; Nzila, A; Ozwara, H (University of NairobiDepartment of Tropical and Infectious Diseases, Institute of Primate Research, Karen, Nairobi, Kenya, 2013)Drug resistance against first-line antimalarials warrants search for new lead compounds and repurposing of drugs such as methotrexate. Animal models are required for preclinical drug development before clinical testing. ...