dc.contributor.author | Wambui, A. | |
dc.contributor.author | Odhiambo, A. | |
dc.contributor.author | Achieng, L. | |
dc.contributor.author | Otieno, C.F | |
dc.contributor.author | Bhatt, S.M | |
dc.date.accessioned | 2018-06-20T12:21:10Z | |
dc.date.available | 2018-06-20T12:21:10Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Wambui A, ODHIAMBO A, Achieng L, Otieno CF, Bhatt SM. "Prevalence of Vitamin D Deficiency in Adult Human
Immunodeficiency Virus Infected Persons at District Hospital in Nairobi, Kenya." IOSR Journal of Dental and Medical Sciences (IOSR-JDMS). 2018;17(3):70-75. | en_US |
dc.identifier.uri | http://hdl.handle.net/11295/103465 | |
dc.description.abstract | Abstract:
Background
:
The
increased availability of
highly active
antiretroviral therapy
(HAART) for Human
immunodeficiency virus (
HIV
)
infected
patients
has led to
significant
reduction in
mortality. However,
there is
increasing evidence t
hat stable HIV positive patients on
HAART
have chronic underlying inflammation. This
leads to premature
age associated non
-
Acquired immunodeficiency syndrome (
AIDS
)
related events.
Vitamin D
deficiency
(VDD)
in HIV positive patients has been associated wit
h disease progression
, chronic
non
-
communicable
diseases
and increased
mortality. Both
HIV
and HAART
have been shown to increase
the risk of
VDD
.
Furthermore, s
upplementation of vitamin D has been shown to reduce
HAART
related bone mineral
density
loss by
up to
50%
.
Objective:
To
determine the prevalence of vitamin D def
iciency in
adult
HIV
infected persons
at
Mbagathi
district hospital.
Design:
Hospital
based cross sectional descriptive study
.
Setting:
Comprehensive
C
are
C
linic
at Mbagathi district
hospita
l located in Nairobi County.
Subjects:
128 HIV infected
persons
who gave consent.
R
esults:
68% of the p
atients were fe
males. The mean age was
41
years.
Eight (
6.3%)
patients were classified as
vitamin D d
eficient
25 hydroxyvitamin D (
25(OH)
D) <
20 ng/ml
, whil
e
thirty
-
eight
(29.7%)
had vitamin D
insufficiency
25(OH)D 21
-
29 ng/ml
and
eighty
-
two (
6
4%) patients
had normal
levels
25(OH)D 30
-
100 ng/ml
.
HAART
naïve patients were 5.3 times more lik
ely to have VDD
.
We did not find any associations betwe
en
vitamin D and a
ge, gender, body mass index
(BMI)
, WHO stage
and
estimated glomerular filtration rate
(eGFR)
. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Nairobi | en_US |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
dc.subject | Conclusion: Prevalence of Vitamin D deficiency was found to be low in our study population | en_US |
dc.title | Prevalence Of Vitamin D Deficiency In Adult Human
Immunodeficiency Virus Infected Persons At District Hospital In Nairobi, Kenya | en_US |
dc.type | Article | en_US |