Browsing BioMedical Journal Articles by Title
Now showing items 33-52 of 201
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Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines
(2009-11-13)Abstract Background An organic extract of the recreational herb khat (Catha edulis Forsk.) triggers cell death in various ... -
CD26/ dipeptidyl peptidase IV (CD26/DPPIV) is highly expressed in peripheral blood of HIV-1 exposed uninfected Female sex workers
(2010-11-25)Abstract Background Design of effective vaccines against the human immunodeficiency virus (HIV-1) continues to present formidable challenges. However, individuals who are exposed HIV-1 but do not get infected may reveal ... -
Characterisation of community acquired non-typhoidal Salmonella from bacteraemia and diarrhoeal infections in children admitted to hospital in Nairobi, Kenya
(2006-12-15)Abstract Background In sub-Saharan Africa community-acquired non-typhoidal Salmonella (NTS) is a major cause of high morbidity ... -
Chloroquine-resistant Plasmodium vivax malaria in Debre Zeit, Ethiopia
(2008-10-29)Abstract Background Plasmodium vivax accounts for about 40% of all malaria infection in Ethiopia. Chloroquine (CQ) is the ... -
Clinical Chemistry Profiles In Injection Heroin Users From Coastal Region, Kenya.
(University of Nairobi, 2014-07)Background Although the co-burden of injection drug use and HIV is increasing in Africa, little is known about the laboratory markers of injection drug use and anti-retroviral treatment (ART) in Kenyan injection drug ... -
The clinical education partnership initiative: an innovative approach to global health education
(University of Nairobi, 2014-12-30)BackgroundDespite evidence that international clinical electives can be educationally and professionally beneficial to both visiting and in-country trainees, these opportunities remain challenging for American residents ... -
Cognitive deficits following exposure to Pneumococcal Meningitis: An Event-Related Potential study
(2012-03-31)Abstract Background Pneumococcal meningitis (PM) is a severe and life-threatening disease that is associated with cognitive impairment including learning difficulties, cognitive slowness, short-term memory deficits and ... -
Comment on “Encephalopathy in patients with COVID‐19: A review”
(John Wiley & Sons, 2020-06-30) -
Community perceptions of health insurance and their preferred design features: implications for the design of universal health coverage reforms in Kenya
(2013-11-12)Abstract Background Health insurance is currently being considered as a mechanism for promoting progress to universal health coverage (UHC) in many African countries. The concept of health insurance ... -
Comparative evaluation of the Ifakara tent trap-B, the standardized resting boxes and the human landing catch for sampling malaria vectors and other mosquitoes in urban Dar es Salaam, Tanzania
(2009-08-12)Frequent, sensitive and accurate sampling of Anopheles mosquitoes is a prerequisite for effective management of malaria vector control programmes. The most reliable existing means to measure mosquito density is the human ... -
Comparative evaluation of three PCR based diagnostic assays for the detection of pathogenic trypanosomes in cattle blood
(2008-12-24)Abstract Currently, several PCR based diagnostic assays have been developed to improve the detection of pathogenic trypanosomes. These tests include use of species specific primers, single and ... -
Comparative performance of the Mbita trap, CDC light trap and the human landing catch in the sampling of Anopheles arabiensis, An. funestusand culicine species in a rice irrigation in western Kenya
(2005-01-25)Mosquitoes sampling is an important component in malaria control. However, most of the methods used have several shortcomings and hence there is a need to develop and calibrate new methods. The Mbita trap for capturing ... -
Correlation of EGFR, pEGFR and p16INK4 expressions and high risk HPV infection in HIV/AIDS-related squamous cell carcinoma of conjunctiva
(2014-02-26)Abstract Background Squamous cell carcinoma of conjunctiva has increased tenfold in the era of HIV/AIDS. The disease pattern has also changed in Africa, affecting young persons, ... -
Costs and cost-effectiveness of delivering intermittent preventive treatment for malaria through schools in western Kenya
(2008-09-30)Abstract Background Awareness of the potential impact of malaria among school-age children has stimulated investigation into malaria interventions that can be delivered ... -
A cross-sectional study of depression with comorbid substance use dependency in pregnant adolescents from an informal settlement of Nairobi: drawing implications for treatment and prevention work
(Springer Nature, 2018-12-20)Introduction Adolescent pregnancy is a highly prevalent and significant public health problem in Kenya, and mental health needs of pregnant adolescent girls have been overlooked. Nearly, 50% of the world’s population ... -
Cytochrome P450 2B6 genetic variants are associated with plasma nevirapine levels and clinical response in HIV-1 infected Kenyan women: a prospective cohort study
(2015-04-15)Abstract Background Polymorphisms in cytochrome P450 2B6 (CYP2B6) affect the steady state plasma concentration of nevirapine. CYP2B6 516G>T and 983T>C are common in African ... -
Decomposing Kenyan socio-economic inequalities in skilled birth attendance and measles immunization
(2013-01-07)Abstract Introduction Skilled birth attendance (SBA) and measles immunization reflect two aspects of a health system. In Kenya, their national coverage gaps are substantial but could be largely ... -
Determinants of health insurance ownership among South African women
(2005-02-28)Abstract Background Studies conducted in developed countries using economic models show that individual- and household- level ... -
Development of environmental tools for Anopheline larval control
(2011-07-06)Abstract Background Malaria mosquitoes spend a considerable part of their life in the aquatic stage, rendering them vulnerable to interventions directed to aquatic habitats. Recent successes of mosquito larval ...