Browsing BioMedical Journal Articles by Title
Now showing items 123-142 of 201
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P16-15. Epitope mapping of HIV-specific CD8+ T-cells responses by polyfunctional and proliferation responses reveal distinct specificity defined by function
(2009-10-22)Background Recent failures of HIV vaccine candidates aimed at inducing protective cellular immunity highlight our need to better characterize responses that are effective in slowing progression to AIDS. Previous work ... -
Parasite accumulation in placenta of non-immune baboons during Plasmodium knowlesi infection
(2015-03-18)Abstract Background Placental malaria (PM) causes adverse pregnancy outcomes in the mother and her foetus. It is difficult to study PM directly in humans due to ethical ... -
Parasites and vectors of malaria on Rusinga Island, Western Kenya
(2015-04-28)Abstract Background There is a dearth of information on malaria endemicity in the islands of Lake Victoria in western Kenya. In this study malaria prevalence and Plasmodium ... -
Participation of African social scientists in malaria control: identifying enabling and constraining factors
(2004-12-06)Abstract Objective To examine the enabling and constraining factors that influence African social scientists involvement in ... -
Pattern, knowledge and practices of HbA1C testing among diabetic patients in a Kenyan tertiary referral hospital
(2013-11-05)Abstract Background Glycated haemoglobin (HbA1C) measurement is the currently accepted gold standard biochemical indicator of long-term glycemic control in diabetic patients. The level of knowledge ... -
Pentoxifylline as an adjunct therapy in children with cerebral malaria
(2010-12-21)Abstract Background Pentoxifylline (PTX) affects many processes that may contribute to the pathogenesis of severe malaria and it has been shown to reduce the duration of coma in children with cerebral malaria. This pilot ... -
Perspectives and concerns of clients at primary health care facilities involved in evaluation of a national mental health training programme for primary care in Kenya
(2013-01-23)Abstract Background A cluster randomised controlled trial (RCT) of a national Kenyan mental health primary care training programme demonstrated a significant impact on the health, disability and ... -
Pharmacological evidence for the folk use of Nefang: antipyretic, anti-inflammatory and antinociceptive activities of its constituent plants
(2015-06-09)Abstract Background Nefang is a polyherbal anti-malarial composed of Mangifera indica ( MiB and MiL; bark and leaf), Psidium guajava ( ... -
Phenotypic characterization of HIV-specific CD8 T cells during acute infant HIV infection
(2009-07-22)Although CD8(+) T cells play an important role in the containment of adult HIV-1 replication, their role in infant HIV-1 infection is not as well understood. Impaired HIV-specific CD8(+) T cell responses may underlie the ... -
Plant use of the Maasai of Sekenani Valley, Maasai Mara, Kenya
(2006-05-05)Abstract Traditional plant use is of tremendous importance in many societies, including most rural African communities. This knowledge is however, rapidly dwindling due to changes towards a more ... -
Practicing provider-initiated HIV testing in high prevalence settings: Consent concerns and missed preventive opportunities
(2011-04-21)Abstract Background Counselling is considered a prerequisite for the proper handling of testing and for ensuring effective HIV preventive efforts. HIV testing services have recently been scaled up substantially with a ... -
Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic
(2012-07-28)Abstract Background CCR5 antagonists have clinically been approved for prevention or treatment of HIV/AIDS. Countries in Sub-Saharan Africa with the highest burden of HIV/AIDS ... -
Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic
(2012-07-28)Abstract Background CCR5 antagonists have clinically been approved for prevention or treatment of HIV/AIDS. Countries in Sub-Saharan Africa with the highest burden of HIV/AIDS are due to adopt ... -
Predictors of mortality in HIV-1 infected children on antiretroviral therapy in Kenya: a prospective cohort
(2010-05-18)Abstract Background Among children, early mortality following highly active antiretroviral therapy (HAART) remains high. It ... -
Prevalence and determinants of unintended pregnancy among women in Nairobi, Kenya
(2013-03-19)Abstract Background The prevalence of unintended pregnancy in Kenya continues to be high. The 2003 Kenya Demographic and Health Survey (KDHS) showed that nearly 50% of unmarried women aged ... -
Prevalence and risk factors of three curable sexually transmitted infections among women in Nairobi, Kenya
(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812604/, 2016-03)Background Sexually transmitted infections (STIs) are a major public health problem, especially in developing countries. The complications of untreated STIs in the female genital tract and their role in adverse pregnancy ... -
Prevalence of hearing loss in children following bacterial meningitis in a tertiary referral hospital.
(University of Nairobi, 2014-03)OBJECTIVE: To establish the proportion of children who develop sensorineural hearing loss after bacterial meningitis and to correlate such loss with patient factors. STUDY DESIGN: Retrospective case review. SETTI ...