dc.contributor.author | Mwachaka, P. | |
dc.contributor.author | Amayo, A. | |
dc.contributor.author | Mwang’ombe, N. | |
dc.contributor.author | Kitunguu, P | |
dc.date.accessioned | 2021-07-29T06:18:08Z | |
dc.date.available | 2021-07-29T06:18:08Z | |
dc.date.issued | 2021-03-03 | |
dc.identifier.citation | Mwachaka, P., Amayo, A., Mwang’ombe, N., & Kitunguu, P. (2021). Association Between Serum Sodium Abnormalities and Clinicoradiologic Parameters in Severe Traumatic Brain Injury. Annals of African Surgery, 18(3), 155–162. | en_US |
dc.identifier.uri | https://www.ajol.info/index.php/aas/article/view/210984 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke/handle/11295/155066 | |
dc.description.abstract | Background: Secondary brain insults after traumatic
brain injury such as electrolyte dysfunctions are
associated with poor outcomes. This study aimed at
determining the incidence of serum sodium ion
abnormalities and their association with clinicoradiological parameters. Methods: A prospective crosssectional study of one hundred and seventeen patients
with severe head injury. Data collected included patient
demographics, prehospital interventions, clinical
examination findings, computed tomography (CT) scan
head findings, serum sodium ion levels (at admission
and 48 h later), and outcome (30 days). Results: At
admission, 93(79.5%) patients had normal serum
sodium ion levels. However, 48 h post-admission,
hypernatremia was prevalent in 56(63.6%) patients (p <
0.001). Hypernatremia was significantly associated with
the use of mannitol (p = 0.036), lower Glasgow Coma
Score (p = 0.047), higher Injury Severity Score (p =
0.015), presence of subdural hematoma (p = 0.044),
midline shift >5 mm (p = 0.048), compressed/absent
basal cistern (p = 0.010), and higher Rotterdam CT
Score (p = 0.003). Hypernatremia reported 48 h postadmission was associated with a high 30-day mortality
rate [odds ratio (OR) 3.55, p = 0.0095]. Risk of mortality
associated with hyponatremia and hypernatremia at
admission was not statistically significant. Conclusion:
While both hyponatremia and hypernatremia can occur
in serious TBI patients, hypernatremia predominates 48
hours post-admission and is associated with statistically
significant increased risk of death. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Annals of African Surgery | en_US |
dc.subject | Traumatic brain injury, hyponatremia, hypernatremia, outcomes, clinico-radiologic parameters | en_US |
dc.title | Association Between Serum Sodium Abnormalities and Clinicoradiologic Parameters in Severe Traumatic Brain Injury | en_US |
dc.type | Article | en_US |