Preclinical efficacy testing of three antivenoms against Naja ashei venom-induced lethality
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Date
2022-04Author
Okumu, Mitchel O
Mbaria, James M
Gikunju, Joseph K
Mbuthia, Paul G
Madadi, Vincent O
Ochola, Francis O
Maloba, Kenneth N
Nderitu, Joseph G
Type
ArticleLanguage
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This study aimed to determine the efficacy of Inoserp, Vins bioproducts, and South African Institute of Medical Research (SAIMR) polyvalent antivenoms in neutralizing Naja ashei venom-induced lethality in mice. The neutralization efficacy of the antivenoms were expressed as effective dose, median effective ratio, potency, normalized potency, volume, and the number of vials of antivenom required to neutralize 100 mg of Naja ashei venom (NAV).
Citation
Okumu MO, Mbaria JM, Gikunju JK, Mbuthia PG, Madadi VO, Ochola FO, Maloba KN, Nderitu JG. Preclinical efficacy testing of three antivenoms against Naja ashei venom-induced lethality. Toxicon X. 2022 Apr 27;14:100124. doi: 10.1016/j.toxcx.2022.100124. PMID: 35518711; PMCID: PMC9065424.Publisher
University of Nairobi
Rights
Attribution-NonCommercial-NoDerivs 3.0 United StatesUsage Rights
http://creativecommons.org/licenses/by-nc-nd/3.0/us/Collections
- Faculty of Health Sciences (FHS) [10378]
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