dc.contributor.author | Fonck K | |
dc.contributor.author | Kaul R. | |
dc.contributor.author | Kimani J | |
dc.contributor.author | Keli F. | |
dc.contributor.author | MacDonald KS. | |
dc.contributor.author | Ronald AR. | |
dc.contributor.author | Plummer, FA | |
dc.contributor.author | Kirui P. | |
dc.contributor.author | Bwayo, JJ | |
dc.contributor.author | Ngugi, Elizabeth N | |
dc.contributor.author | Moses S. | |
dc.contributor.author | Temmerman, M | |
dc.date.accessioned | 2013-04-17T07:07:16Z | |
dc.date.available | 2013-04-17T07:07:16Z | |
dc.date.issued | 2000 | |
dc.identifier.citation | Int J STD AIDS. 2000 Dec;11(12):804-11 | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/11138916 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16204 | |
dc.description.abstract | Our objectives were to describe the baseline findings of a trial of antibiotic prophylaxis to prevent sexually transmitted infections (STIs) and HIV-1 in a cohort of Nairobi female sex workers (FSWs). A questionnaire was administered and a medical examination was performed. HIV-negative women were randomly assigned to either one gram azithromycin or placebo monthly. Mean age of the 318 women was 32 years, mean duration of sex work 7 years and mean number of clients was 4 per day. High-risk behaviour was frequent: 14% practised anal intercourse, 23% sex during menses, and 3% used intravenous drugs. While 20% reported condom use with all clients, 37% never use condoms. However, STI prevalence was relatively low: HIV-1 27%, bacterial vaginosis 46%, Trichomonas vaginalis 13%, Neisseria gonorrhoeae 8%, Chlamydia trachomatis 7%, syphilis 6% and cervical intraepithelial neoplasia (CIN) 3%. It appears feasible to access a population of high-risk FSWs in Nairobi with prevention programmes, including a proposed trial of HIV prevention through STI chemoprophylaxis | en |
dc.language.iso | en | en |
dc.title | A randomized, placebo-controlled trial of monthly azithromycin prophylaxis to prevent sexually transmitted infections and HIV-1 in Kenyan sex workers: study design and baseline findings | en |
dc.type | Article | en |
local.publisher | International Center for Reproductive Health, Department of Obstetrics and Gynaecology, Ghent University, Belgium. | en |
local.publisher | Department of Community Health, University of Nairobi, | en |
local.publisher | Department of Medical Microbiology, University of Nairobi | en |
local.publisher | Department of Public Health, Nairobi City Council | en |
local.publisher | Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada | en |