dc.contributor.author | Onyango, GK | |
dc.date.accessioned | 2013-05-23T12:47:37Z | |
dc.date.available | 2013-05-23T12:47:37Z | |
dc.date.issued | 1986 | |
dc.identifier.citation | Master Of Medicine In Obstetrics And Gynaecology | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/24918 | |
dc.description.abstract | Tamoxifen is pure anti-estrogen free from demonstrable intrinsic estrogenic activity in men. Eleven patients were treated with 20mg
of Tamoxifen given orally as a single daily dose. Three of these had persistent oligospermia after surgical treatment for varicocele; the other eight patients had no demonstrable cause for the oligospermia and were considered as idiopathic. The treatment was continued for
a period of six months. In all the patients there was a significant increase in the total sperm output per ejaculate and the sperm concentration after 3 months or more. The hormone levels were also increased above the basal levels throughout the period of drug intake.
So far no pregnacies have been reported; however considering the increase in the sperm output per ejaculate after giving the drug; tamoxifen can be considered a valuable drug for treatment of Oligospermia.
INTRODUCTION
The incidence of male factor in infertile couples as seen in the hospital clinics has been reported from many areas to be between 5 to 40% (i,2,3). In United States of America 'a similar incidence is reported (4). Nasak reported also similar findings in Cameroon (5).
Infertility consumes a large proportion of reproductive health services in developing countries. About 30 to 40% of consultations of the family planning clinic or gynaecologic clinics relate to complaints of infertility (5). | en |
dc.language.iso | en | en |
dc.publisher | University Of Nairobi | en |
dc.title | Treatment of oligospermia with tamoxifen at Kenyatta National Hospital | en |
dc.type | Thesis | en |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |
local.publisher | Department of Medicine | en |