Oral squamous cell carcinoma in human immunodeficiency virus positive patients: clinicopathological audit
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Date
2012-03Author
Butt, FM
Chindia, ML
Rana, F
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
BACKGROUND:
Most human immunodeficiency virus positive patients now have a longer life expectancy, with the advent of highly active antiretroviral therapy. However, they are now at increased risk of developing a malignancy during their lives.
AIM:
To investigate the age at which oral squamous cell carcinoma presents in patients infected with human immunodeficiency virus.
STUDY DESIGN:
Prospective, clinicohistopathological audit of patients infected with human immunodeficiency virus.
RESULTS:
Of 200 human immunodeficiency virus positive patients, 16 (8 per cent) presented with oral squamous cell carcinoma (nine women and seven men; age range 18-43 years, mean age 31.7 years). The majority of patients (62.5 per cent) had stage III and IV disease (tumour-node-metastasis staging). There was a predilection for poorly differentiated oral squamous cell carcinoma (using Broder's histopathological classification).
CONCLUSION:
Oral squamous cell carcinoma associated with human immunodeficiency virus infection appears to present at a relatively young age.
Citation
F M A BUTT, M L CHINDIA, RANA F. 2012. Oral squamous cell carcinoma in human immunodeficiency virus positive patients: clinicopathological audit. The Journal of Laryngology & Otology. n/a(126):276-278Publisher
University of Nairobi College of Health Science