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The Discovery of GS-9669, a Thumb Site II Non-nucleoside Inhibitor of NS5B for the Treatment of Genotype 1 Chronic Hepatitis C Infection
(University of Nairobi, 2013-11-06)
Investigation of thiophene-2-carboxylic acid HCV NS5B site II inhibitors, guided by measurement of cell culture medium binding, revealed the structure-activity relationships for intrinsic cellular potency. The pharmacokinetic ...
Coverage of HIV Prevention Services for Female Sex Workers in Seven Cities of Myanmar.
(Population Services International-Myanmar, Yangon,, 2013)
Cross-sectional surveys of female sex workers using time-location sampling in seven cities of
Myanmar gauged coverage of HIV prevention programs. HIV testing in last year ranged from 28
to 73 %; attending peer educator ...
Introduction of a sexual health practice nurse is associated with increased STI testing of men who have sex with men in primary care
(2013)
BACKGROUND:
The study objective was to investigate the effect of the introduction of a sexual health practice nurse on HIV and STI testing in a general practice that specialized in gay men's health.
METHODS:
This ...
Assessment of strategies for male involvement in the prevention of mother-to-child transmission of HIV services in Blantyre, Malawi.
(2013)
BACKGROUND:
Despite the documented benefits of prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) services, the uptake remains low in sub-Saharan Africa. The lack of male involvement ...
Global estimates of syphilis in pregnancy and associated adverse outcomes: analysis of multinational antenatal surveillance data.
(2013)
BACKGROUND:
The World Health Organization initiative to eliminate mother-to-child transmission of syphilis aims for ≥ 90% of pregnant women to be tested for syphilis and ≥ 90% to receive treatment by 2015. We calculated ...
Consultations for sexually transmitted infections in the general practice in the Netherlands: an opportunity to improve STI/HIV testing.
(BMJ, 2013)
OBJECTIVES:
In the Netherlands, sexually transmitted infection (STI) care is provided by general practitioners (GPs) as well as by specialised STI centres. Consultations at the STI centres are monitored extensively, but ...
Decline in the prevalence of HIV and sexually transmitted infections among female sex workers in Benin over 15 years of targeted interventions.
(Wolters Kluwer, 2013)
BACKGROUND:
An HIV-preventive intervention targeting the sex work milieu and involving fully integrated components of structural interventions, communication for behavioral change and care for sexually transmitted ...
Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya
(University of Nairobi, 2013-12)
ETHNOPHARMACOLOGICAL RELEVANCE:
Traditional medicine plays a critical role in treatment of chronic debilitating and life threatening conditions and diseases. Cancer is one such condition whose therapeutic intervention ...
Neurological syndrome in an HIV-prevention trial participant randomized to daily tenofovir disoproxil fumarate (300 mg) and emtricitabine (200 mg) in Bondo, Kenya
(University of Nairobi, 2013-11)
Side effects of antiretroviral drug use by HIV-positive patients have been extensively studied; however, there are limited data on the side effects of antiretroviral drugs used as an HIV prophylaxis among healthy, HIV-negative ...
The Future Of Organizations: Musings Of A Manager
(University of Nairobi,, 2013)
Dominant forces of the last century, developments in science and technology, the presence of ideological rigidities and the complexity of organizational environment will continually shape the future. Developments in human ...