| dc.contributor.author | P, Daisy | |
| dc.contributor.author | R, Jasmine | |
| dc.contributor.author | S, Ignacimuthu | |
| dc.contributor.author | E, Murugan | |
| dc.date.accessioned | 2013-07-11T06:56:59Z | |
| dc.date.available | 2013-07-11T06:56:59Z | |
| dc.date.issued | 2009-03 | |
| dc.identifier.citation | P. Daisy, R. Jasmine, S. Ignacimuthu, E. Murugan;A novel Steroid1 from Elephantopus scaber L. an Ethnomedicinal plant with antidiabetic activity ;Phytomedicine, Volume 16, Issues 2–3, March 2009, Pages 252–257;http://dx.doi.org/10.1016/j.phymed.2008.06.001 | en |
| dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S0944711308001074 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/47282 | |
| dc.description.abstract | Acetone extract of Elephantopus scaber, an ethnomedicnal plant, reduced the blood glucose levels in streptozotocin-induced diabetic rats significantly. Acute toxicity studies revealed the non-toxic nature of the crude extract. Fractionation of the acetone extract yielded a new steroid, 28Nor-22(R)Witha 2,6,23-trienolide. Biological testing of the compound demonstrated a significant antidiabetic activity by reducing the elevated blood glucose levels and restoring the insulin levels in streptozotocin-induced diabetic rats. This compound can be a useful candidate to treat diabetes. | en |
| dc.language.iso | en | en |
| dc.publisher | University of Nairobi | en |
| dc.subject | Streptozotocin;Elephantopus scaber;Diabetes;Bioactivity;Fractionation;28Nor-22(R)Witha 2,6,23-trienolide | en |
| dc.title | A novel Steroid1 from Elephantopus scaber L. an Ethnomedicinal plant with antidiabetic activity | en |
| dc.type | Article | en |
| local.publisher | College of Biological and Physical Sciences | en |
