Superficial spreading malignant melanoma with neurosarcomatous metastasis
![Thumbnail](/bitstream/handle/11295/53739/Abstract.pdf.jpg?sequence=4&isAllowed=y)
View/ Open
Date
1986Author
Nyong'o, Aggrey O
Manop, Huntrakoon
Parsa, Cyrus
Raja, Abdul
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
A case of neurosarcomatous nodal metastasis of superficial spreading malignant melanoma, without primary site desmoplasia or sarcomatous changes, is reported. Of particular interest regarding the metastasis are: the ultrastructural demonstration of numerous cytoplasmic microtubules, absence of premeianosomes, intense immunohistochemical reaction with S-100 protein antibody, and the presence, at the light microscopic level, of extranodal fibrosis. The primary lesion shows a preexisting benign nevus and features suggestive of lamellar fibroplasia. The origin and histogenesis of melanocytic desmoplasia, in the context of a neural crest progenitor cell, and of lamellar fibroplasia, are discussed.
URI
http://informahealthcare.com/doi/abs/10.3109/00313028609087572http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/53739
Citation
1986, Vol. 18, No. 4 , Pages 473-477Publisher
University of Nairobi Department of Human Pathology
Collections
- Faculty of Health Sciences (FHS) [10387]