Schistosoma mansoni morbidity among school-aged children:a SCORE project in Kenya
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Date
2012-11Author
Samuels, AM
Matey, E
Mwinzi, PN
Wiegand, RE
Muchiri, G
Ireri, E
Hyde, M
Montgomery, SP
Karanja, DM
Secor, WE
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Schistosomiasis control programs aim to reduce morbidity but are evaluated by infection prevalence and intensity reduction. We present baseline cross-sectional data from a nested cohort study comparing indicators of morbidity for measuring program impact. Eight hundred twenty-two schoolchildren 7-8 years of age from Nyanza Province, Kenya, contributed stool for diagnosis of Schistosoma mansoni and soil-transmitted helminths (STH) and blood smears for malaria, and were evaluated for anemia, quality of life, exercise tolerance, anthropometry, and ultrasound abnormalities. Schistosoma mansoni, STH, and malaria infection prevalence were 69%, 25%, and 8%, respectively. Only anemia and S. mansoni infection (adjusted odds ratio [aOR] = 1.70; confidence interval [CI] = 1.03-2.80), and hepatomegaly and heavy S. mansoni infection (aOR = 2.21; CI = 1.19-4.11) were associated. Though anemia and hepatomegaly appeared most useful at baseline, additional morbidity indicators may be sensitive longitudinal measures to evaluate schistosomiasis program health impact.
URI
http://www.ncbi.nlm.nih.gov/pubmed/22987651http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/57616
Citation
Samuels AM, Matey E, Mwinzi PN, Wiegand RE, Muchiri G, Ireri E, Hyde M, Montgomery SP, Karanja DM, Secor WE. Schistosoma mansoni morbidity among school-aged children: a SCORE project n Kenya.Am J Trop Med Hyg. 2012 NOV;87 (5) :874-82Publisher
University of Nairobi School of Public Health
Collections
- Faculty of Health Sciences (FHS) [10387]