dc.contributor.author | Mutai, C | |
dc.contributor.author | Rukunga, G | |
dc.contributor.author | Vagias, C | |
dc.contributor.author | Roussis, V | |
dc.date.accessioned | 2013-10-25T06:19:59Z | |
dc.date.available | 2013-10-25T06:19:59Z | |
dc.date.issued | 2007 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/20162054 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816603/ | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/57872 | |
dc.description.abstract | The activities of total extracts and lupane triterpenes, isolated from the stem bark of Acacia mellifera, were evaluated against Plasmodium berghei strain ANKA in a female Swiss mouse model. Five isolated compounds and the crude extracts were evaluated for antimalarial activity and Quinine hydrochloride was used as a positive control. Only betulin and the methanolic extract produced considerable antimalarial activity in mice infected with P. berghei parasites. This study demonstrated the presence of bioactive agents in Acacia mellifera. | en |
dc.language.iso | en | en |
dc.title | In vivo screening of antimalarial activity of Acacia mellifera (Benth) (Leguminosae) on Plasmodium berghei in mice. | en |
dc.type | Article | en |