Incident Herpes Simplex Virus Type 2 Infection Increases the Risk of Subsequent Episodes of Bacterial Vaginosis.
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Date
2013-11Author
Masese, L
Baeten, JM
Richardson, BA
Bukusi, E
John-Stewart, G
Jaoko, W
Shafi, J
Kiarie, J
McClelland, RS.
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Herpes simplex virus type 2 (HSV-2) infected women have a higher prevalence of bacterial vaginosis (BV) compared to HSV-2-seronegative women. To explore the temporal association between these conditions, we evaluated the frequency of BV episodes before and after HSV-2 acquisition in a prospective study of 406 HSV-2/HIV-1-seronegative Kenyan women, of whom 164 acquired HSV-2. Incident HSV-2 was associated with increased likelihood of BV (adjusted OR 1.28; 95% CI 1.05-1.56; p=0.01). Our findings strengthen the evidence for a causal link between genital HSV-2 infection and disruption of the vaginal microbiota.
URI
http://www.ncbi.nlm.nih.gov/pubmed/24273042http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/60992
Citation
J Infect Dis. 2013 Nov 22. [Epub ahead of print]Publisher
University of Nairobi Department of Medical Microbiology
Collections
- Faculty of Health Sciences (FHS) [10387]