Browsing Journal Articles by Author "Tang, J"
Now showing items 1-3 of 3
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CD4:CD8 lymphocyte ratio as a quantitative measure of immunologic health in HIV-1 infection: findings from an African cohort with prospective data.
Tang, J; Li, X; Price, MA,; Sanders, EJ; Anzala, O; Karita, E; Kamali, A; Lakhi, S; Allen, S; Hunter, E (University of Nairobi, 2015-07)In individuals with human immunodeficiency virus type 1 (HIV-1) infection, CD4:CD8 lymphocyte ratio is often recognized as a quantitative outcome that reflects the critical role of both CD4(+) and CD8(+) T-cells in HIV-1 ... -
Dynamics of viremia in primary HIV-1 infection in Africans: Insights from analyses of host and viral correlates.
Prentice, HA; Price, MA; Porter, TR,; Cormier, E; Mugavero, MJ; Kamali, A; Karita, E; Lakhi, S; Sanders, EJ; Anzala, O; Amornkul, PN; Allen, S; Hunter, E; Kaslow, RA,; Gilmour, J; Tang, J; IAVI Africa HIV Prevention Partnership (University of Nairobi, 2014)In HIV-1 infection, plasma viral load (VL) has dual implications for pathogenesis and public health. Based on well-known patterns of HIV-1 evolution and immune escape, we hypothesized that VL is an evolving quantitative ... -
Human leukocyte antigen variants B*44 and B*57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub-Saharan Africans with several viral subtypes
Anzala, Aggrey O.; Tang, J; Cormier, J; Price, M A; Prentice, H A; Song, W; Kamali, A; Karita, E; Lakhi, S (University of nairobiCollege of health science, 2011)As part of an ongoing study of early human immunodeficiency virus type 1 (HIV-1) infection in sub-Saharan African countries, we have identified 134 seroconverters (SCs) with distinct acute-phase (peak) and early chronic-phase ...