Browsing Journal Articles by Author "Tariq M."

Now showing items 1-2 of 2

    • Beta-2 adrenergic receptor genotypes and haplotypes in different ethnic groups 

      Indalo AA.; Maxwell TJ.; Ameyaw MM.; Pritchard S.; Thornton N.; Folayan G.; Githang'a Jessie N.; Tariq M.; Mobarek A.; Evans DA.; Ofori-Adjei D.; Templeton AR.; McLeod HL. (University of Nairobi.Department of Clinical Pharmacology, College of Health Sciences, University of Nairobi, 2005-10)
      The human beta-2 adrenergic receptor (beta2AR) is responsible for the binding of endogenous catecholamines and their exogenously administered agonists and antagonists. Three functional polymorphisms in codons 16, 27 and ...

    • MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity. 

      Ameyaw MM.; Regateiro F.; Li T.; Liu X.; Tariq M.; Mobarek A.; Thornton N.; Folayan GO.; Githang'a Jessie N.; Indalo A.; Fori-adjei D.; Price-evans DA.; Mcleod HL. (University of NairobiDepartment of Human Panthology, 2001-04)
      P-glycoprotein (PGP), the product of the multidrug resistance gene (MDR1), acts as an energy-dependent efflux pump that exports its substrates out of the cell. PGP expression is an important factor regulating absorption ...